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视神经循环与眼压:视网膜中央动脉和睫状后短动脉的作用及其对氧张力的影响。

Optic nerve circulation and ocular pressure: contribution of central retinal artery and short posterior ciliary arteries and the effect on oxygen tension.

作者信息

Armaly M F, Araki M

出版信息

Invest Ophthalmol. 1975 Jun;14(6):475-9.

PMID:1132944
Abstract

Blood-flow rate in the optic nerve of the rhesus monkey 4 mm. behind the globe monitored by the heated thermocouple and tissue p02 measurement is found to be influenced by ocular pressure level. Ligation of central retinal artery reduced flow rate to 79 per cent of normal but did not influence the effect of IOP on blood-flow rate. Ligation of short posterior ciliary arteries reduced blood-flow rate to 21 per cent of normal and virtually eliminated the IOP effect. Raising IOP to above systolic arterial pressure level reduced blood-flow rate to 17 per cent of normal. At IOP levels greater than 50 mm. Hg, the reduction in blood-flow rate and in Po becomes marked and may be sufficient to produce primary lesions at this site.

摘要

通过加热热电偶和组织氧分压测量监测发现,恒河猴眼球后4毫米处视神经的血流速率受眼压水平影响。结扎视网膜中央动脉可使血流速率降至正常的79%,但不影响眼压对血流速率的作用。结扎睫状后短动脉可使血流速率降至正常的21%,并几乎消除了眼压的影响。将眼压升高至收缩期动脉压水平以上,可使血流速率降至正常的17%。当眼压高于50毫米汞柱时,血流速率和氧分压的降低变得明显,可能足以在该部位产生原发性病变。

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引用本文的文献

1
Role of axoplasmic transport in the pathophysiology of ischaemic disc swelling.轴浆运输在缺血性视盘肿胀病理生理学中的作用。
Br J Ophthalmol. 1980 Apr;64(4):247-61. doi: 10.1136/bjo.64.4.247.
2
Methods for determination of optic nerve blood flow.视神经血流的测定方法。
Yale J Biol Med. 1988 Jan-Feb;61(1):51-60.