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[在胸主动脉手术期间进行脑脊液引流和深度全身低温并完全停止循环以保护脊髓]

[Cerebrospinal fluid drainage and deep systemic hypothermia with total absence of circulation for spinal cord protection during surgery on the thoracic aorta].

作者信息

Fernández Suárez F, Sánchez Burón J, Sánchez García V, Martín Moreno M, Fernández-Vega Sanz M, Brid Castañón T

机构信息

Servicio de Anestesiología y Reanimación. Hospital General de Asturias, Hospital Centra, Oviedo.

出版信息

Rev Esp Anestesiol Reanim. 2001 Apr;48(4):192-5.

Abstract

A 53-yearold man with a dissecting aneurysm of Stanford's type-B or Crawford's type I measuring 8.5 cm in diameter underwent replacement of the distal descending aorta and the thoracic aorta using techniques for spinal cord protection involving deep hypothermia at 17 degrees C and lasting 38 minutes with total absence of circulation. A subarachnoid catheter was inserted at the lumbar level to monitor spinal fluid pressure as well as to provide drainage if pressure exceeded 10 mm Hg. During surgery 60 ml was drained, followed by 95 ml after surgery on the same day and 325, 262 and 169 ml on the following three days. No signs of neurological deficit were observed during the postoperative period. Clinical course was good until hypovolemic shock developed 27 days after the operation due to upper digestive tract bleeding caused by two duodenal ulcers that perforated the gastroduodenal artery. Emergency antrectomy and vagotomy were performed. The patient died from multiple organ failure. Spinal cord injury continues to be one of the most feared complications after excision of thoracic and thoracoabdominal aorta aneurysm. Currently, various ways of protecting the spinal cord are practiced, including drainage of cerebrospinal fluid, partial bypass of the femoral artery, intercostal artery reimplantation, drug therapy and local spinal and/or systemic hypothermia. These methods, together with shorter clamping time have achieved a reduction in the incidence of spinal cord injuries.

摘要

一名53岁男性,患有直径8.5厘米的斯坦福B型或克劳福德I型夹层动脉瘤,接受了远端降主动脉和胸主动脉置换术,采用了脊髓保护技术,包括17摄氏度的深度低温,持续38分钟,完全无循环。在腰椎水平插入蛛网膜下腔导管,以监测脑脊液压力,并在压力超过10毫米汞柱时进行引流。手术期间引流60毫升,术后当天引流95毫升,随后三天分别引流325、262和169毫升。术后未观察到神经功能缺损的迹象。临床过程良好,直到术后27天因十二指肠溃疡穿孔导致胃十二指肠动脉出血引发低血容量性休克。进行了急诊胃窦切除术和迷走神经切断术。患者死于多器官功能衰竭。脊髓损伤仍然是胸主动脉和胸腹主动脉瘤切除术后最令人担忧的并发症之一。目前,人们采用了各种保护脊髓的方法,包括脑脊液引流、股动脉部分旁路、肋间动脉再植、药物治疗以及局部脊髓和/或全身低温。这些方法,再加上缩短夹闭时间,已使脊髓损伤的发生率有所降低。

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