Zanetti S, Spanu T, Deriu A, Romano L, Sechi L A, Fadda G
Dipartimento di Scienze Biomediche, Università degli studi di Sassari, Viale S. Pietro 43b, 07100, Sassari, Italy.
Int J Antimicrob Agents. 2001 May;17(5):407-9. doi: 10.1016/s0924-8579(01)00307-7.
Bacteria of the genus Vibrio include harmless aquatic strains as well as strains capable of causing epidemics of cholera and human intestinal diseases. Some of these species may show resistance to different antibiotics including cefotaxime, tetracycline and chloramphenicol. The susceptibility to different antibiotics was tested using 40 Vibrio alginolyticus, eight V. parahaemolyticus and six V. vulnificus strains isolated in the coastal waters of Northern Sardinia (Italy). The frequency of resistance to beta-lactams was unexpectedly high. More than 80% of Vibrio isolates were resistant to ampicillin and 2.5% of V. alginolyticus were resistant to ceftazidime and cefotetan. Forty percent of V. alginolyticus and three V. vulnificus isolates gave a positive nitrocefin test. PCR was also performed using selected primers chosen for having common sequences of bla(TEM) and bla(SHV) genes.
弧菌属细菌包括无害的水生菌株以及能够引发霍乱流行和人类肠道疾病的菌株。其中一些物种可能对包括头孢噻肟、四环素和氯霉素在内的不同抗生素表现出抗性。使用从意大利撒丁岛北部沿海水域分离出的40株溶藻弧菌、8株副溶血性弧菌和6株创伤弧菌菌株，测试了它们对不同抗生素的敏感性。对β-内酰胺类抗生素的耐药频率出乎意料地高。超过80%的弧菌分离株对氨苄西林耐药，2.5%的溶藻弧菌对头孢他啶和头孢替坦耐药。40%的溶藻弧菌和3株创伤弧菌分离株的硝基头孢菌素试验呈阳性。还使用为具有bla(TEM)和bla(SHV)基因的共同序列而选择的引物进行了聚合酶链反应(PCR)。
