Richards Donald E, King Kathryn E, Ait-Ali Tahar, Harberd Nicholas P
Department of Molecular Genetics, John Innes Centre, Colney Lane, Norwich NR4 7UJ, United Kingdom; e-mail:
Annu Rev Plant Physiol Plant Mol Biol. 2001 Jun;52:67-88. doi: 10.1146/annurev.arplant.52.1.67.
Gibberellins are hormones that control growth and a wide variety of other plant developmental processes. In recent years, significant progress has been made on the biochemistry of gibberellin biosynthesis and on the mechanisms by which gibberellin levels are regulated in plants. There have also been major advances in the understanding of gibberellin signaling, with several key genes being cloned. This review discusses our current understanding of gibberellin signaling, as seen from the perspective of molecular genetic analysis, and relates these observations to previous biochemical studies. In particular, we highlight an important conclusion of recent years: that GAI/RGA and orthologs play major roles in gibberellin signaling in diverse plant species, and that gibberellin probably stimulates growth by derepression of GAI/RGA.
赤霉素是一类控制植物生长及多种其他发育过程的激素。近年来，在赤霉素生物合成的生物化学以及植物中赤霉素水平调控机制方面取得了显著进展。在赤霉素信号传导的理解上也有重大进展，多个关键基因已被克隆。本综述从分子遗传学分析的角度讨论了我们目前对赤霉素信号传导的理解，并将这些观察结果与先前的生物化学研究相关联。特别是，我们强调近年来的一个重要结论：GAI/RGA及其直系同源基因在多种植物物种的赤霉素信号传导中起主要作用，并且赤霉素可能通过解除对GAI/RGA的抑制来刺激生长。
