5-羟色胺刺激丽蝇离体唾液腺时的膜通透性变化。
Membrane permeability changes during stimulation of isolated salivary glands of Calliphora by 5-hydroxytryptamine.
作者信息
Berridge M J, Lindley B D, Prince W T
出版信息
J Physiol. 1975 Jan;244(3):549-67. doi: 10.1113/jphysiol.1975.sp010812.
Abstract
- The membrane resistance of isolated salivary glands was found to decrease in response to 5-HT. The change in resistance was calcium-dependent. 2. The resistance change of the apical membrane was found to be much greater than the change in resistance of the basal membrane. 3. Potential responses under current-clamped conditions showed that one part of the biphasic response to 5-HT (attributed to an increase in chloride permeability) could be reversed and the other part (attributed to an increase in a potassium pump) could not. 4. These observations have been incorporated into a model which, on evaluation, predicts all of the observed potential changes during the action of 5-HT. It suggests that the potential responses reflect changes in the internal chloride concentration produced by the calcium-dependent increases in chloride permeability.
摘要
- 研究发现，分离出的唾液腺的膜电阻会因5-羟色胺（5-HT）而降低。电阻变化依赖于钙。2. 发现顶端膜的电阻变化远大于基底膜的电阻变化。3. 在钳制电流条件下的电位反应表明，对5-HT双相反应的一部分（归因于氯离子通透性增加）可以逆转，而另一部分（归因于钾泵增加）则不能。4. 这些观察结果已被纳入一个模型，经评估，该模型预测了5-HT作用期间所有观察到的电位变化。这表明电位反应反映了由氯离子通透性的钙依赖性增加所导致的细胞内氯离子浓度的变化。
相似文献
1
Membrane permeability changes during stimulation of isolated salivary glands of Calliphora by 5-hydroxytryptamine.5-羟色胺刺激丽蝇离体唾液腺时的膜通透性变化。
J Physiol. 1975 Jan;244(3):549-67. doi: 10.1113/jphysiol.1975.sp010812.
2
Studies on the mechanism of fluid secretion by isolated salivary glands of Calliphora.关于丽蝇离体唾液腺液体分泌机制的研究。
J Exp Biol. 1976 Apr;64(2):311-22. doi: 10.1242/jeb.64.2.311.
3
The effects of 5-hydroxytryptamine and cyclic AMP on the potential profile across isolated salivary glands.5-羟色胺和环磷酸腺苷对离体唾液腺跨膜电位分布的影响。
J Exp Biol. 1972 Apr;56(2):323-33. doi: 10.1242/jeb.56.2.323.
4
Receptor turnover and the action of 5-hydroxytryptamine on the salivary glands of the blowfly Calliphora erythrocephala, the housefly Musca domestica and frog skin epithelium.受体更新以及5-羟色胺对红头丽蝇、家蝇唾液腺和蛙皮肤上皮的作用。
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987;88(2):233-9. doi: 10.1016/0742-8413(87)90115-0.
5
Activation of the cyclic AMP pathway promotes serotonin-induced Ca2+ oscillations in salivary glands of the blowfly Calliphora vicina.环腺苷酸途径的激活促进了丽蝇唾液腺中 5-羟色胺诱导的 Ca2+ 振荡。
Cell Calcium. 2013 Feb;53(2):94-101. doi: 10.1016/j.ceca.2012.10.004. Epub 2012 Nov 4.
6
The role of cyclic nucleotides and calcium in the regulation of chloride transport.环核苷酸和钙在氯化物转运调节中的作用。
Ann N Y Acad Sci. 1980;341:156-71. doi: 10.1111/j.1749-6632.1980.tb47170.x.
7
Ion-selective electrode studies on the effects of 5-hydroxytryptamine on the intracellular level of potassium in an insect salivary gland.离子选择电极法研究5-羟色胺对昆虫唾液腺细胞内钾离子水平的影响。
J Exp Biol. 1978 Feb;72:203-16. doi: 10.1242/jeb.72.1.203.
8
Relationship between latency and period for 5-hydroxytryptamine-induced membrane responses in the Calliphora salivary gland.家蝇唾液腺中5-羟色胺诱导的膜反应的潜伏期与周期之间的关系。
Biochem J. 1994 Sep 1;302 ( Pt 2)(Pt 2):545-50. doi: 10.1042/bj3020545.
9
Cellular mode of serotonin action on Cl- transport in the rabbit corneal epithelium.血清素对兔角膜上皮细胞氯离子转运的细胞作用模式
Biochim Biophys Acta. 1984 Nov 21;778(1):139-43. doi: 10.1016/0005-2736(84)90457-7.
10
Effect of neural stimulation on acinar cell membrane potentials in isolated pancreas and salivary gland segments.神经刺激对离体胰腺和唾液腺组织腺泡细胞膜电位的影响。
Membr Biochem. 1980;3(1-2):49-66. doi: 10.3109/09687688009063878.
引用本文的文献
1
When a Discovery Is a Rediscovery: Do We Know the History of Our Own Subject?当一项发现实为重新发现时：我们了解自己学科的历史吗？
Function (Oxf). 2021 Jun 8;2(4):zqab030. doi: 10.1093/function/zqab030. eCollection 2021.
2
Ca2+ and cAMP signaling pathways interact to increase the diuretic effect of serotonin in Malpighian tubules of the kissing bug. Focus on "Serotonin triggers cAMP- and PKA-1-mediated intracellular calcium waves in Malpighian tubules of Rhodnius prolixus".钙离子（Ca2+）信号通路与环磷酸腺苷（cAMP）信号通路相互作用，增强了猎蝽马氏管中5-羟色胺的利尿作用。重点关注“5-羟色胺触发致倦库蚊马氏管中cAMP和蛋白激酶A-1介导的细胞内钙波”。
Am J Physiol Regul Integr Comp Physiol. 2014 Oct 1;307(7):R819-21. doi: 10.1152/ajpregu.00336.2014. Epub 2014 Aug 20.
3
KCl Transport across an insect epithelium: II. electrochemical potentials and electrophysiology.氯化钾在昆虫上皮组织中的转运：II. 电化学势与电生理学
J Membr Biol. 1984;80(1):27-47. doi: 10.1007/BF01868688.
4
cAMP potentiates InsP3-induced Ca2+ release from the endoplasmic reticulum in blowfly salivary glands.环磷酸腺苷（cAMP）增强了丽蝇唾液腺内质网中由肌醇三磷酸（InsP3）诱导的钙离子释放。
BMC Physiol. 2008 May 20;8:10. doi: 10.1186/1472-6793-8-10.
5
cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands.环磷酸腺苷（cAMP）调节丽蝇唾液腺中质膜液泡型氢离子-ATP酶的组装和活性。
Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3926-31. doi: 10.1073/pnas.0600011103. Epub 2006 Feb 28.
6
New light shed on fluid formation in the seminiferous tubules of the rat.大鼠生精小管中液体形成的新见解。
J Physiol. 2002 Jul 15;542(Pt 2):445-52. doi: 10.1113/jphysiol.2002.018648.
7
Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(-) channels in pancreatic acinar cells.笼锁Ca(2+)的局部解笼锁揭示了胰腺腺泡细胞中Ca(2+)激活的Cl(-)通道的分布。
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10948-53. doi: 10.1073/pnas.181353798. Epub 2001 Sep 4.
8
Serotonin-induced intercellular calcium waves in salivary glands of the blowfly Calliphora erythrocephala.血清素诱导红头丽蝇唾液腺中的细胞间钙波。
J Physiol. 1997 Apr 1;500 ( Pt 1)(Pt 1):17-28. doi: 10.1113/jphysiol.1997.sp021995.
9
Electrophysiological properties of resting secretory membranes of lamellibranch mantles. Interaction between calcium and potassium.瓣鳃类外套膜静息分泌膜的电生理特性。钙与钾之间的相互作用。
J Gen Physiol. 1980 Jan;75(1):21-37. doi: 10.1085/jgp.75.1.21.
10
A novel effect of cobalt treatment on calcium-dependent responses of the cockroach salivary gland.钴处理对蟑螂唾液腺钙依赖性反应的一种新效应。
Experientia. 1980 Jan 15;36(1):98-9. doi: 10.1007/BF02003998.
本文引用的文献
1
The site of the stimulatory action of vasopressin on sodium transport in toad bladder.血管加压素对蟾蜍膀胱钠转运的刺激作用部位。
J Gen Physiol. 1968 May;51(5):589-605. doi: 10.1085/jgp.51.5.589.
2
Effects of noradrenaline on potassium reflux, membrane potential and electrolyte levels in tissue slices prepared from guinea-pig liver.去甲肾上腺素对豚鼠肝脏制备的组织切片中钾反流、膜电位和电解质水平的影响。
J Physiol. 1972 Sep;225(3):721-50. doi: 10.1113/jphysiol.1972.sp009966.
3
Pancreatic acinar cells: membrane potential and resistance change evoked by acetylcholine.胰腺腺泡细胞：乙酰胆碱引起的膜电位和电阻变化
J Physiol. 1974 Apr;238(1):145-58. doi: 10.1113/jphysiol.1974.sp010515.
4
Conductance changes associated with the secretory potential in the cockroach salivary gland.蟑螂唾液腺中与分泌电位相关的电导变化。
J Physiol. 1974 Feb;236(3):723-31. doi: 10.1113/jphysiol.1974.sp010462.
5
Transepithelial potential changes during stimulation of isolated salivary glands with 5-hydroxytryptamine and cyclic AMP.用5-羟色胺和环磷酸腺苷刺激离体唾液腺时的跨上皮电位变化。
J Exp Biol. 1972 Feb;56(1):139-53. doi: 10.1242/jeb.56.1.139.
6
The effects of 5-hydroxytryptamine and cyclic AMP on the potential profile across isolated salivary glands.5-羟色胺和环磷酸腺苷对离体唾液腺跨膜电位分布的影响。
J Exp Biol. 1972 Apr;56(2):323-33. doi: 10.1242/jeb.56.2.323.
7
Role of calcium and adenosine-3':5'-cyclic monophosphate in controlling fly salivary gland secretion.钙和3':5'-环磷酸腺苷在控制果蝇唾液腺分泌中的作用。
Proc Natl Acad Sci U S A. 1972 Mar;69(3):553-7. doi: 10.1073/pnas.69.3.553.
8
The role of 5-hydroxytryptamine and cyclic AMP in the control of fluid secretion by isolated salivary glands.5-羟色胺和环磷酸腺苷在离体唾液腺液体分泌控制中的作用。
J Exp Biol. 1970 Aug;53(1):171-86. doi: 10.1242/jeb.53.1.171.
9
Insect salivary glands: stimulation of fluid secretion by 5-hydroxytryptamine and adenosine-3',5'-monophosphate.昆虫唾液腺：5-羟色胺和3',5'-环磷酸腺苷对液体分泌的刺激作用
Science. 1968 Oct 25;162(3852):462-3. doi: 10.1126/science.162.3852.462.
Zotero 插件