Corina D P, Richards T L, Serafini S, Richards A L, Steury K, Abbott R D, Echelard D R, Maravilla K R, Berninger V W
Department of Radiology, University of Washington, Box 357115, University of Washington, Seattle, WA 98195-7115, USA.
Neuroreport. 2001 May 8;12(6):1195-201. doi: 10.1097/00001756-200105080-00029.
During fMRI, dyslexic and control boys completed auditory language tasks (judging whether pairs of real and/or pseudo words rhymed or were real words) in 30 s 'on' conditions alternating with a 30 s 'off' condition (judging whether tone pairs were same). During phonological judgment, dyslexics had more activity than controls in right than left inferior temporal gyrus and in left precentral gyrus. During lexical judgment, dyslexics were less active than controls in bilateral middle frontal gyrus and more active than controls in left orbital frontal cortex. Individual dyslexics were reliably less active than controls in left insula and left inferior temporal gyrus. Dyslexic and control children differ in brain activation during auditory language processing skills that do not require reading.
在功能磁共振成像（fMRI）过程中，患有阅读障碍的男孩和对照组男孩在30秒的“开启”状态下完成听觉语言任务（判断真实和/或伪词对是否押韵或是否为真实单词），并与30秒的“关闭”状态（判断声调对是否相同）交替进行。在语音判断过程中，阅读障碍者右侧颞下回和左侧中央前回的活动比对照组更多。在词汇判断过程中，阅读障碍者双侧额中回的活动比对照组少，而左侧眶额皮质的活动比对照组多。个体阅读障碍者在左侧脑岛和左侧颞下回的活动比对照组明显更少。患有阅读障碍的儿童和对照组儿童在不需要阅读的听觉语言处理技能方面，大脑激活情况存在差异。
