Maeda H, Nakamura M, Negi A
Department of Ophthalmology, Kobe University, Japan.
Eye (Lond). 2001 Apr;15(Pt 2):163-7. doi: 10.1038/eye.2001.53.
The changes in short wavelength sensitive (S-) cone electroretinograms (ERGs) to ganzfeldt flash stimuli were examined in patients with Posner-Schlossman syndrome to study the differences in S-cone action in both the acute attack phase and the remission phase.
Ganzfeldt colour flashes under bright white background illumination were used to elicit short wavelength (S-), and mixed long- (L) and middle- (M) wavelength sensitive cone ERGs. Three subjects with unilateral Posner-Schlossman syndrome and 18 age-matched normal controls were compared. To compare the media opacity we obtained the L,M-cone balance, namely, the log density units of the neutral density filter required to produce the L,M-cone b-wave elicited with red stimuli which is identical to those with blue stimuli.
Selective reduction of the S-cone ERG b-wave in acute attacks of Posner-Schlossman syndrome was found. Two of three cases showed the recovery of the S-cone b-wave with a decrease in the intraocular pressure. With regard to the implicit time, significant delay of the S-cone b-wave could not be detected in all subjects.
Selective reduction of the S-cone component of the ERG during raised intraocular pressure was found. The S-cone pathway is thought to be more vulnerable to damage than the L,M-cone systems following elevations of intraocular pressure.
研究波斯纳 - 施洛斯曼综合征患者短波长敏感（S）-视锥细胞视网膜电图（ERG）对全视野闪光刺激的变化，以探讨急性发作期和缓解期S视锥细胞功能的差异。
在明亮白色背景照明下使用全视野彩色闪光来诱发短波长（S）以及混合的长（L）和中（M）波长敏感视锥细胞ERG。比较了3名单侧波斯纳 - 施洛斯曼综合征患者和18名年龄匹配的正常对照者。为了比较介质混浊度，我们获得了L、M视锥细胞平衡，即产生与蓝色刺激相同的红色刺激诱发的L、M视锥细胞b波所需的中性密度滤光片的对数密度单位。
发现在波斯纳 - 施洛斯曼综合征急性发作期S视锥细胞ERG的b波有选择性降低。3例中有2例随着眼压降低S视锥细胞b波恢复。关于潜伏期，在所有受试者中均未检测到S视锥细胞b波有明显延迟。
发现在眼压升高期间ERG的S视锥细胞成分有选择性降低。眼压升高后，S视锥细胞通路被认为比L、M视锥细胞系统更容易受到损害。
