Yamamoto S, Nitta K, Kamiyama M
Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
Vision Res. 1997 Aug;37(15):2157-9. doi: 10.1016/s0042-6989(96)00303-3.
The cone electroretinograms (ERGs) to different chromatic stimuli were recorded in myopic subjects. Ganzfeld color flashes under bright white background illumination were used to elicit short-wavelength-sensitive (S-), and mixed long-(L-) and middle-(M-) wavelength-sensitive cone ERGs. Nineteen subjects with mild myopia (between -3.0 and -6.0 D), 12 subjects with high myopia (greater than -6.25 D) but without chorioretinal atrophy or posterior staphyloma, and 22 age-matched normal controls were compared. The S-cone and L,M-cone b-wave amplitudes decreased progressively with increasing myopia. The amplitudes of the S-cone and the L,M-cone b-wave were significantly lower in highly myopic subjects, as compared with controls. The implicit times of both b-waves were normal in most myopic subjects. The S-cone and the L,M-cone ERGs were almost equally affected in myopic eyes. The selective reduction of the S-cone pathway in high myopia, reported previously, may not originate from the other retina.
在近视受试者中记录了对不同颜色刺激的圆锥视网膜电图（ERG）。在明亮的白色背景照明下，使用全视野彩色闪光来诱发短波敏感（S-）以及混合的长波（L-）和中波（M-）敏感圆锥ERG。比较了19名轻度近视（-3.0至-6.0 D之间）的受试者、12名高度近视（大于-6.25 D）但无脉络膜视网膜萎缩或后巩膜葡萄肿的受试者以及22名年龄匹配的正常对照者。随着近视程度增加，S圆锥和L、M圆锥b波振幅逐渐降低。与对照组相比，高度近视受试者的S圆锥和L、M圆锥b波振幅显著更低。大多数近视受试者中两种b波的潜伏时间均正常。近视眼中S圆锥和L、M圆锥ERG受影响程度几乎相同。先前报道的高度近视中S圆锥通路的选择性降低可能并非源于视网膜其他部位。
