小口病患者正常的S视锥细胞视网膜电图b波。
Normal S cone electroretinogram b-wave in Oguchi's disease.
作者信息
Yamamoto S, Hayashi M, Takeuchi S, Shirao Y, Kita K, Kawasaki K
机构信息
Toho University Sakura Hospital, Japan.
出版信息
Br J Ophthalmol. 1997 Dec;81(12):1043-5. doi: 10.1136/bjo.81.12.1043.
AIM
The short wavelength sensitive (S) cone electroretinograms (ERGs) were examined in two patients with Oguchi's disease to study S cone function.
METHODS
Ganzfeld colour flashes under bright white background illumination were used to elicit S cone, and mixed long (L) and middle (M) wavelength sensitive cone ERGs.
RESULTS
The S cone ERG b-wave was normal with short wavelength stimuli with normal L and M cone responses in both patients.
CONCLUSIONS
These ERG results indicate that the S cone system as well as the L and M cone system is not defective in Oguchi's disease, while the S cone responses are not detectable in the complete type of congenital stationary night blindness as reported previously. The results imply that there is a significant difference in the way the S cone system is affected in different forms of stationary night blindness, and that the S cone and rod do not share the same arrestin system.
目的
对两名小口氏病患者进行短波长敏感（S）视锥细胞视网膜电图（ERG）检查，以研究S视锥细胞功能。
方法
在明亮的白色背景照明下使用全视野彩色闪光来诱发S视锥细胞以及混合的长（L）和中（M）波长敏感视锥细胞ERG。
结果
两名患者在短波长刺激下S视锥细胞ERG的b波正常，L和M视锥细胞反应正常。
结论
这些ERG结果表明，小口氏病中S视锥细胞系统以及L和M视锥细胞系统均无缺陷，而如先前报道，在完全型先天性静止性夜盲中无法检测到S视锥细胞反应。结果表明，在不同形式的静止性夜盲中，S视锥细胞系统受影响的方式存在显著差异，并且S视锥细胞和视杆细胞不共享相同的抑制蛋白系统。
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