Haverstock B D
Division of Podiatric Surgery, Department of Surgery, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.
Clin Podiatr Med Surg. 2001 Jan;18(1):147-59.
Excessive scarring caused by pathologically overabundant collagen deposition is a problem known by all surgeons. Complications to wound healing, such as hypertrophic scars and keloids, can lead to an aesthetically unacceptable result or even lead to anatomic dysfunction. An overwhelming amount of hypotheses concerning treatment of these problems is available. There seems to be no absolutely effective treatment for hypertrophic scars and keloids and the number of treatment modalities illustrate the lack of understanding concerning this kind of pathologic scar healing. Most studies reported have not been well controlled and have produced conflicting results.
病理性胶原蛋白过度沉积导致的过度瘢痕形成是所有外科医生都熟知的问题。伤口愈合的并发症,如增生性瘢痕和瘢痕疙瘩,可能导致美学上无法接受的结果,甚至导致解剖功能障碍。关于这些问题的治疗有大量的假说。对于增生性瘢痕和瘢痕疙瘩似乎没有绝对有效的治疗方法,而且治疗方式的数量表明对这种病理性瘢痕愈合缺乏了解。大多数已报道的研究控制不佳,结果相互矛盾。