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肥厚性瘢痕与瘢痕疙瘩。

Hypertrophic scars and keloids.

作者信息

Haverstock B D

机构信息

Division of Podiatric Surgery, Department of Surgery, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.

出版信息

Clin Podiatr Med Surg. 2001 Jan;18(1):147-59.

PMID:11344975
Abstract

Excessive scarring caused by pathologically overabundant collagen deposition is a problem known by all surgeons. Complications to wound healing, such as hypertrophic scars and keloids, can lead to an aesthetically unacceptable result or even lead to anatomic dysfunction. An overwhelming amount of hypotheses concerning treatment of these problems is available. There seems to be no absolutely effective treatment for hypertrophic scars and keloids and the number of treatment modalities illustrate the lack of understanding concerning this kind of pathologic scar healing. Most studies reported have not been well controlled and have produced conflicting results.

摘要

病理性胶原蛋白过度沉积导致的过度瘢痕形成是所有外科医生都熟知的问题。伤口愈合的并发症,如增生性瘢痕和瘢痕疙瘩,可能导致美学上无法接受的结果,甚至导致解剖功能障碍。关于这些问题的治疗有大量的假说。对于增生性瘢痕和瘢痕疙瘩似乎没有绝对有效的治疗方法,而且治疗方式的数量表明对这种病理性瘢痕愈合缺乏了解。大多数已报道的研究控制不佳,结果相互矛盾。

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Hypertrophic scars and keloids.肥厚性瘢痕与瘢痕疙瘩。
Clin Podiatr Med Surg. 2001 Jan;18(1):147-59.
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[Comparative study of collagen in hypertrophic and keloid cicatrix].[增生性瘢痕与瘢痕疙瘩中胶原蛋白的比较研究]
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Front Genet. 2022 Jan 3;12:806740. doi: 10.3389/fgene.2021.806740. eCollection 2021.
2
Enhanced keratinocyte proliferation and migration in co-culture with fibroblasts.与成纤维细胞共培养可增强角质形成细胞的增殖和迁移。
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Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing.
无瘢痕与纤维化伤口愈合的细胞和分子特征
Dermatol Res Pract. 2010;2010:790234. doi: 10.1155/2010/790234. Epub 2010 Dec 27.
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Mechanism of benign biliary stricture: a morphological and immunohistochemical study.良性胆管狭窄的机制:一项形态学和免疫组织化学研究。
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