Ellitsgaard V, Ellitsgaard N
Department of Surgery, Naestved County Hospital, Naestved, Denmark.
Acta Chir Plast. 1997;39(3):69-77.
Excess scarring caused by pathologically overabundant collagen deposition is a problem known by all surgeons. Such complications to wound healing known as hypertrophic scars and keloids might turn out aesthetically unacceptable to the patient and some scars might even cause anatomic dysfunction. Reviewing the literature in planning a strategy of treatment the surgeon encounters an overwhelming amount of hypotheses on the topic. There seems to be no absolutely effective treatment for hypertrophic scars and keloids and the number of treatment modalities illustrate the lack of understanding concerning this kind of pathologic scarhealing. Most studies have not been well controlled and have produced conflicting results. This review outlines the nature of hypertrophic scars and keloid. Based on a critical assessment of current treatment modalities some guidelines for the choice of treatment is proposed.
病理性胶原蛋白过度沉积导致的瘢痕过度形成是所有外科医生都熟知的问题。这种被称为增生性瘢痕和瘢痕疙瘩的伤口愈合并发症，在美观上可能让患者无法接受，有些瘢痕甚至可能导致解剖功能障碍。在制定治疗策略时查阅文献，外科医生会遇到关于该主题的大量假说。对于增生性瘢痕和瘢痕疙瘩似乎没有绝对有效的治疗方法，治疗方式的数量表明对这种病理性瘢痕愈合缺乏了解。大多数研究控制不佳，结果相互矛盾。本综述概述了增生性瘢痕和瘢痕疙瘩的本质。基于对当前治疗方式的批判性评估，提出了一些治疗选择的指导原则。
