Grekou Alexandra N., Stravoravdi Pelagia, Patakiouta Frideriki, Toliou Theano
"Theagenio" Cancer Hospital, Thessaloniki, Greece.
Breast J. 1999 Jan;5(1):63-64. doi: 10.1046/j.1524-4741.1999.005001063.x.
Helioid inclusions are single membrane-bounded intranuclear bodies of unknown nature which have been described in a case of breast adenoma, in mammary hyperplasia, and in a case of acinic cell carcinoma of the parotid gland. We report the detection of helioid inclusions in a case of breast carcinoma, which involves a 60-year-old woman with infiltrating ductal breast carcinoma of apocrine type. On electron microscopic examination we observed characteristic intranuclear helioid inclusions in some carcinoma cells. Occasionally intranuclear profiles of dense granules were present, some of which showed a just discernible filamentous border. The significance of these rare ultrastructural inclusions remains to be elucidated.
螺旋体样包涵体是一种性质不明的单膜包被的核内小体，已在一例乳腺腺瘤、乳腺增生以及一例腮腺腺泡细胞癌中被描述。我们报告了在一例乳腺癌中检测到螺旋体样包涵体，该病例为一名60岁患有大汗腺型浸润性导管乳腺癌的女性。电子显微镜检查发现，部分癌细胞中存在特征性的核内螺旋体样包涵体。偶尔可见核内密集颗粒轮廓，其中一些显示出刚可辨别的丝状边界。这些罕见的超微结构包涵体的意义仍有待阐明。
