Wang L, Zhang Z, Qian J
Second Affiliated Hospital, Harbin Medical University, Harbin (150086).
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Mar;18(3):165-7.
To study the effective mechanism of Sancai Fensui Dan in mice.
Sancai injection (SCI) was given to normal or anemia mice and their hemoglobin (Hb), red blood cell (RBC), reticulocyte (Ret) of peripheral blood, mitosis index (MI) of red cells, bone marrow nucleated cell (BMC) were measured. And the cultured hemopoietic progenitor cells of burst forming unit-erythroid (BFU-E) and colony forming unit-erythroid (CFU-E) were used to observe the hemopoiesis effect of SCI.
SCI could promote the increase of Hb, RBC, Ret, MI and BMC in anemia mice. At the presence of spleen cells or macrophages in peritoneal cavity, it could enhance the proliferation of BFU-E and CFU-E.
SCI could promote hemopoiesis by activating the hemo-opsonin.
研究三才粉碎丹对小鼠的作用机制。
将三才注射液（SCI）给予正常或贫血小鼠，检测其外周血血红蛋白（Hb）、红细胞（RBC）、网织红细胞（Ret）、红细胞有丝分裂指数（MI）、骨髓有核细胞（BMC）。并采用培养的红系爆式集落形成单位（BFU-E）和红系集落形成单位（CFU-E）来观察SCI的造血作用。
SCI可促进贫血小鼠Hb、RBC、Ret、MI和BMC的增加。在脾细胞或腹腔巨噬细胞存在的情况下，它可增强BFU-E和CFU-E的增殖。
SCI可通过激活血液调理素促进造血。
