Hilger T M, Smith E M, Ault K
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, USA.
Infect Dis Obstet Gynecol. 2001;9(1):3-8. doi: 10.1155/s1064744901000023.
To determine predictors of Chlamydia trachomatis infection among women 14-24 years of age attending family planning clinics throughout a rural Midwestern state.
The study population included 16,756 women between the ages of 14 and 24 years attending family planning clinics for annual examinations throughout the state of Iowa in 1997. All women under 25 years of age having annual exams were tested for C. trachomatis during the visit. At the time of exam, both behavioral and demographic data were collected on all women participating in the study.
The majority of women in the study (96%) reported no symptoms of chlamydia. Only 2.5% of all women had a positive test result. In the multivariate model, the odds ratios were significantly increased among the youngest age (14-17 years; OR = 2.2), those with mucopurulent cervicitis (OR = 3.4), cervical friability (OR = 2.2), symptomatic for infection (OR = 1.8), risk history (OR = 1.6), and black race (OR = 1.2) and predictive of a C. trachomatis infection.
Risk factors predictive of C. trachomatis infection among younger aged women attending family planning clinics in a Midwest rural population are consistent with predictors of infection among women attending family planning clinics across the United States. The overall findings suggest the importance of developing screening guidelines as a means of lowering chlamydia rates. This may be a particularly difficult task in light of the low rate of symptoms that would lead a woman to seek medical care, even in younger age women who are at higher risk. In addition, screening guidelines would be more difficult to implement in a rural setting.
确定在中西部一个农村州的计划生育诊所就诊的14至24岁女性沙眼衣原体感染的预测因素。
研究人群包括1997年在爱荷华州全州计划生育诊所进行年度检查的16756名14至24岁的女性。所有25岁以下进行年度检查的女性在就诊时都接受了沙眼衣原体检测。在检查时,收集了所有参与研究的女性的行为和人口统计学数据。
研究中的大多数女性(96%)报告无衣原体症状。所有女性中只有2.5%检测结果呈阳性。在多变量模型中,最年轻年龄组(14至17岁;比值比=2.2)、患有黏液脓性宫颈炎的女性(比值比=3.4)、宫颈易脆的女性(比值比=2.2)、有感染症状的女性(比值比=1.8)、有风险史的女性(比值比=1.6)以及黑人女性(比值比=1.2)的比值比显著升高,且可预测沙眼衣原体感染。
在中西部农村人口中,在计划生育诊所就诊的年轻女性沙眼衣原体感染的预测风险因素与美国各地计划生育诊所就诊女性的感染预测因素一致。总体研究结果表明制定筛查指南对于降低衣原体感染率的重要性。鉴于即使在感染风险较高的年轻女性中,导致女性寻求医疗护理的症状发生率较低,这可能是一项特别困难的任务。此外,筛查指南在农村地区更难实施。