Jover-Díaz F, Robert-Gates J, Andreu-Gimenez L, Merino-Sanchez J
Internal Medicine Department, San Juan University Hospital, Alicante, Spain.
Infect Dis Obstet Gynecol. 2001;9(1):47-9. doi: 10.1155/S1064744901000084.
Although the pathogenic role of Coxiella burnetii infection during pregnancy is controversial, some cases of stillbirth and abortion occurring after an acute or chronic infection have been mentioned in the literature. Recently, Q fever has been advocated as a significant cause of morbidity and mortality in pregnancy
We describe an 18-year-old primipara woman admitted to our hospital for high fever and pancytopenia during an acute C. burnetii infection. She was successfully treated with clarithromycin, overcoming fever and pancytopenia. Finally, she gave birth to a healthy infant, and 1 year later both remained well.
Q fever is a potentially serious disease in pregnancy owing to the possibility of placenta infection and fetal transmission affecting its outcome. Q fever infection should be suspected in unexplained febrile episodes or abortion during pregnancy, when epidemiologic and clinical data are present. We believe that C. burnetii serology should be tested in cases of fever of known origin or unexplained abortions, as the TORCH infections are.
尽管伯氏考克斯体感染在孕期的致病作用存在争议，但文献中已提及一些急性或慢性感染后发生死产和流产的病例。最近，Q热被认为是孕期发病和死亡的一个重要原因。
我们描述了一名18岁初产妇，在急性伯氏考克斯体感染期间因高热和全血细胞减少入住我院。她接受克拉霉素治疗后成功康复，发热和全血细胞减少症状消失。最后，她生下一名健康婴儿，1年后两人均状况良好。
由于存在胎盘感染和胎儿传播影响妊娠结局的可能性，Q热在孕期是一种潜在的严重疾病。当出现流行病学和临床数据时，在孕期不明原因的发热发作或流产时应怀疑Q热感染。我们认为，对于已知病因的发热或不明原因流产病例，应像检测TORCH感染一样检测伯氏考克斯体血清学。
