Kornblum C, Broicher R, Walther E, Seibel P, Reichmann H, Klockgether T, Herberhold C, Schröder R
Department of Neurology, University of Bonn, Germany.
Neurology. 2001 May 22;56(10):1409-12. doi: 10.1212/wnl.56.10.1409.
To assess dysphagia, the authors examined 12 patients with Kearns-Sayre syndrome (KSS) or chronic progressive external ophthalmoplegia (CPEO) due to mitochondrial DNA (mtDNA) deletion by videofluoroscopy and manometry. Cricopharyngeal achalasia was documented in nine of 12 patients (75%), whereas deglutitive coordination problems were found in one patient. Cricopharyngeal myotomy may be an effective treatment in selected cases with severe cricopharyngeal obstruction.
为评估吞咽困难情况，作者通过电视荧光吞咽造影检查和测压法，对12例因线粒体DNA（mtDNA）缺失导致的凯-赛综合征（KSS）或慢性进行性外眼肌麻痹（CPEO）患者进行了检查。12例患者中有9例（75%）记录到环咽肌失弛缓症，而仅1例患者存在吞咽协调问题。对于部分存在严重环咽肌梗阻的病例，环咽肌切开术可能是一种有效的治疗方法。
