Geesey G G
Department of Microbiology and Center for Biofilm Engineering, PO Box 173520, Montana State University, Bozeman, Montana 59717-3520, USA.
Curr Opin Microbiol. 2001 Jun;4(3):296-300. doi: 10.1016/s1369-5274(00)00206-x.
Population level studies demonstrate that bacterial colonization of surfaces and subsequent biofilm architecture are controlled by a variety of factors that include the hydrodynamics, surface chemistry and genotype of the cell. New molecular tools now extend our ability to investigate among bacterial cells within a surface-associated population subtle phenotypic differences that do not involve changes in genotype. Such resolution has led to new discoveries in relationships between bacterial cells and their environment.
群体水平研究表明，表面的细菌定殖及随后的生物膜结构受多种因素控制，这些因素包括流体动力学、表面化学性质和细胞的基因型。新的分子工具现在扩展了我们的能力，能够在与表面相关的群体中的细菌细胞之间研究不涉及基因型变化的细微表型差异。这种分辨率已在细菌细胞与其环境之间的关系方面带来了新发现。
