Cederholm M, Sjödén P O, Axelsson O
Department of Women's and Children's Health, Section of Obstetrics and Gynaecology, Uppsala University, Uppsala, Sweden.
Acta Obstet Gynecol Scand. 2001 Jun;80(6):539-45.
The aim was to evaluate the psychological and physical impact on women submitting to early amniocentesis or chorionic villus sampling and their preferences concerning fetal invasive procedures in a forthcoming pregnancy.
Fifty-one women undergoing early amniocentesis or chorionic villus sampling at 10-13 weeks gestation participated. The women completed questionnaires including the Hospital Anxiety and Depression Scale on three occasions: before, immediately after, and one week after the invasive procedure.
The women were more concerned about a spontaneous abortion and waiting for the result than about a possible unreliable result. A majority of the women did not worry about the risk of fetal injury induced by the procedure. More women in the chorionic villus sampling group found the invasive procedure to be physically straining. Two-thirds of the women experienced no or minor psychological strain but one-third experienced major strain. Approximately 20% were classified as doubtful cases and cases of clinical anxiety. Nearly all women would choose to have an invasive procedure of the same kind in a forthcoming pregnancy.
The psychological and physical impact on women undergoing invasive procedures for fetal karyotyping does not constitute a major clinical problem. However, a certain number of women report distress and anxiety which should be attended to by professionals involved in fetal invasive procedures. These women may benefit from more support.
目的是评估接受早期羊膜穿刺术或绒毛取样的女性所受到的心理和身体影响，以及她们对未来妊娠中胎儿侵入性检查的偏好。
51名在妊娠10 - 13周接受早期羊膜穿刺术或绒毛取样的女性参与了研究。这些女性在侵入性检查前、检查后立即以及检查后一周这三个时间点完成了包括医院焦虑抑郁量表在内的问卷调查。
与可能出现不可靠结果相比，女性更担心自然流产和等待检查结果。大多数女性并不担心该检查导致胎儿受伤的风险。绒毛取样组中更多女性觉得侵入性检查对身体有负担。三分之二的女性没有经历或仅经历了轻微的心理压力，但三分之一的女性经历了较大压力。约20%被归类为可疑病例和临床焦虑病例。几乎所有女性在未来妊娠中都会选择进行同类型的侵入性检查。
对接受胎儿核型分析侵入性检查的女性而言，心理和身体影响并非主要临床问题。然而，有一定数量的女性报告了痛苦和焦虑，参与胎儿侵入性检查的专业人员应予以关注。这些女性可能会从更多支持中受益。
