Paget S A, Bulkley B H, Grauer L E, Seningen R
Am J Med. 1975 Jul;59(1):134-9. doi: 10.1016/0002-9343(75)90331-9.
Libman-Sacks endocarditis caused progressive life-threatening mitral regurgitation necessitating mitral valve replacement in an 18 year old woman with systemic lupus erythematosus (SLE). Although Libman-Sacks endocarditis is frequently seen at autopsy in patients with SLE, hemodynamically significant valvular disease due to that lesion is quite rare. We found no previous reports describing mitral regurgitation in a patient with SLE which has necessitated surgical intervention.
利布曼-萨克斯心内膜炎导致一名18岁系统性红斑狼疮（SLE）女性出现进行性危及生命的二尖瓣反流，需要进行二尖瓣置换术。尽管在SLE患者尸检中经常发现利布曼-萨克斯心内膜炎，但该病变导致具有血流动力学意义的瓣膜疾病相当罕见。我们未发现之前有描述SLE患者二尖瓣反流并需要手术干预的报告。
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