Fröberg J E, Karlsson C G, Levi L, Lidberg L
Biol Psychol. 1975;2(3):175-88. doi: 10.1016/0301-0511(75)90018-6.
Circadian rhythms in urinary catecholamine excretion, performance and self-ratings were studied in two experiments with a total of 29 subjects who were deprived of sleep for 72 hr. Adrenaline excretion and fatigue ratings showed the most consistent circadian variations; noradrenaline and performance rhythms were more irregular. The average crest phase for adrenaline excretion was around 1400 hr, for noradrenaline about 0800 hr, for performance 1700 hr and for fatigue 0500 hr. Twenty-four hour levels of performance and 'subjective arousal' decreased over the three days of sleep deprivation, while adrenaline excretion levels increased.
在两项实验中，对总共29名被剥夺睡眠72小时的受试者的尿儿茶酚胺排泄、表现和自我评分的昼夜节律进行了研究。肾上腺素排泄和疲劳评分显示出最一致的昼夜变化；去甲肾上腺素和表现节律则更不规则。肾上腺素排泄的平均峰值相位约在14:00时，去甲肾上腺素约在08:00时，表现为17:00时，疲劳为05:00时。在睡眠剥夺的三天中，24小时的表现水平和“主观觉醒”下降，而肾上腺素排泄水平上升。
