Salama Guy, Choi Bum-Rak
Department of Cell Biology and Physiology at the University of Pittsburgh School of Medicine, 3500 Terrace Street, Pittsburgh, PA 15261.
News Physiol Sci. 2000 Feb;15:33-41. doi: 10.1152/physiologyonline.2000.15.1.33.
Activation and repolarization across mammalian hearts follow complex three-dimensional pathways that are governed by fiber structure, intercellular coupling, and action potentials (APs) with spatially heterogeneous properties. Voltage-sensitive dyes and imaging techniques offer new insights on how spatiotemporal heterogeneities of APs govern propagation, repolarization, and AV node conduction and help us visualize arrhythmias with previously unattainable details.
