Biino G, Rezzani C, Grassi M, Marinoni A
Department of Applied Health Sciences, University of Pavia, Italy.
J Outcome Meas. 2000;4(4):740-62.
Univocal definition and classification of Asthma have always been a matter of discussion, and that is reflected in the difficulty of constructing a measure of pathology severity. The European Community Health Survey is a multinational survey designed to compare the prevalence of asthma in subjects, aged 20 to 44 years, in several European areas. In each participating center a sample of 3000 adults filled a self-administered screening questionnaire composed by 9 dichotomous items. Aim of the present study is to investigate unidimensionality of the ECRHS screening questionnaire and to determine and validate a scoring of asthma-like symptoms seriousness. Dimensionality and scoring was determined through a Homogeneity Analysis by Alternating Least Square; while scoring validation was assessed by a cross validation technique. This study found the existence of a sole dimension underlying the screening questionnaire; furthermore a scoring of asthma-like symptoms seriousness was determined with the indication of a cut-off in order to distinguish between asthma symptomatic and non symptomatic subjects.
哮喘的统一界定和分类一直是个讨论的话题，这也反映在构建病理严重程度衡量标准的困难上。欧洲共同体健康调查是一项多国调查，旨在比较欧洲几个地区20至44岁人群中哮喘的患病率。在每个参与中心，3000名成年人的样本填写了一份由9个二分项目组成的自我管理筛查问卷。本研究的目的是调查欧洲共同体健康调查筛查问卷的单维度性，并确定和验证哮喘样症状严重程度的评分。通过交替最小二乘法的同质性分析确定维度和评分；而评分验证则通过交叉验证技术进行评估。本研究发现筛查问卷背后存在单一维度；此外，还确定了哮喘样症状严重程度的评分，并给出了区分哮喘有症状和无症状受试者的临界值。
