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猴脑室周围白质软化症中星形胶质细胞的嗜苏丹性脂质蓄积。

Sudanophilic lipid accumulation in astrocytes in periventricular leukomalacia in monkeys.

作者信息

Sumi S M

出版信息

Acta Neuropathol. 1979 Aug;47(3):241-3. doi: 10.1007/BF00690553.

DOI:10.1007/BF00690553
PMID:113976
Abstract

Sudanophilic lipid accumulation is a characteristic feature of periventircular leukomalacia (PVL) of infants. At least two types of lipid-containing cells have been identified, one being the macrophage, the other the "pre-myelin glial cell". A third type of lipid-containing cell has been seen in two monkeys with spontaneous PVL. Electron microscopically this cell appears to be an astrocyte. This probably represents a reaction of the astrocyte to hypoxia and may be the equivalent of the "hypertrophic" astrocytes found in human infants.

摘要

嗜苏丹性脂质蓄积是婴儿脑室周围白质软化症(PVL)的一个特征性表现。至少已鉴定出两种含脂质细胞,一种是巨噬细胞,另一种是“前髓鞘神经胶质细胞”。在两只患有自发性PVL的猴子中发现了第三种含脂质细胞。在电子显微镜下,这种细胞似乎是星形胶质细胞。这可能代表星形胶质细胞对缺氧的反应,可能等同于在人类婴儿中发现的“肥大”星形胶质细胞。

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本文引用的文献

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THE FINE STRUCTURE OF ASTROCYTES IN THE CEREBRAL CORTEX AND THEIR RESPONSE TO FOCAL INJURY PRODUCED BY HEAVY IONIZING PARTICLES.大脑皮层星形细胞的精细结构及其对重离子致局灶损伤的反应。
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Changes in glial cells during human telencephalic myelinogenesis.
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