McArdle N, Kingshott R, Engleman H M, Mackay T W, Douglas N J
University Department of Medicine, Royal Perth Hospital, GPO Box X2213, Perth, Western Australia 6847, Australia.
Thorax. 2001 Jul;56(7):513-8. doi: 10.1136/thorax.56.7.513.
The sleep apnoea/hypopnoea syndrome (SAHS) causes snoring, apnoeas, and restlessness during sleep which partners frequently complain about. A study was undertaken to determine the impact on partners of SAHS and of treatment of the patient with continuous positive airway pressure (CPAP).
Forty nine partners and patients with SAHS booked for CPAP treatment completed in house and validated questionnaires (Pittsburgh sleep quality index, Short Form 36 self-reported health status) before the patient started treatment. Twenty three couples in whom the index SAHS patient had no driving problems were recruited to a randomised crossover trial with 1 month limbs of CPAP and placebo capsule. At the end of each limb the partners' sleep was monitored by home polysomnography (PSG) and questionnaires were completed.
Before treatment partners frequently reported moderate to severe disturbance from patient snoring/apnoeas/restlessness and had poor sleep quality and self-reported health status. In the crossover study (22 completed) the partners' objective sleep quality did not differ between CPAP and placebo, but they reported benefit from treatment of the patients with CPAP in subjective sleep quality (p=0.05) and disturbance to sleep (p=0.03). The reported change in partners' sleep quality between pre-study and following CPAP treatment correlated positively with CPAP use (r=0.5, p=0.01).
Partners of patients with SAHS have poor sleep quality and self-reported health status but only subjective sleep quality benefits from treatment of the patient with CPAP.
睡眠呼吸暂停/低通气综合征(SAHS)会导致睡眠期间打鼾、呼吸暂停和不安,伴侣经常对此抱怨。开展了一项研究以确定SAHS对伴侣的影响以及持续气道正压通气(CPAP)治疗患者的效果。
49名预约进行CPAP治疗的SAHS患者及其伴侣在患者开始治疗前完成了院内验证问卷(匹兹堡睡眠质量指数、简短健康调查问卷36项自评健康状况)。招募了23对索引SAHS患者无驾驶问题的夫妇参加一项随机交叉试验,试验分为CPAP和安慰剂胶囊两个为期1个月的阶段。在每个阶段结束时,通过家庭多导睡眠图(PSG)监测伴侣的睡眠情况并完成问卷。
治疗前,伴侣经常报告因患者打鼾/呼吸暂停/不安而受到中度至重度干扰,睡眠质量差且自评健康状况不佳。在交叉研究(22例完成)中,CPAP和安慰剂组伴侣的客观睡眠质量无差异,但他们报告CPAP治疗患者对主观睡眠质量(p=0.05)和睡眠干扰(p=0.03)有改善。报告的伴侣在研究前和CPAP治疗后的睡眠质量变化与CPAP使用呈正相关(r=0.5,p=0.01)。
SAHS患者的伴侣睡眠质量差且自评健康状况不佳,但只有主观睡眠质量能从CPAP治疗患者中获益。