Yee A G, Revel J P
J Cell Biol. 1975 Jul;66(1):200-4. doi: 10.1083/jcb.66.1.200.
In the course of a freeze-cleave study on intercellular junctions in the regenerating rat liver, we observed an unusual array of intramembranous particles located in regions of contact between endothelial cells lining the hepatic sinusoids. These arrays were characterized by an accumulation of particles which resembled a zonula occludens in their linear deployment but differed in that the contact regions were composed of individual particles which remained separated from each other by regular particle-free intervals.
在对再生大鼠肝脏细胞间连接进行冷冻蚀刻研究的过程中,我们观察到肝血窦内皮细胞接触区域存在一系列异常的膜内颗粒。这些颗粒排列的特征是颗粒聚集,其线性分布类似于紧密连接,但不同之处在于接触区域由单个颗粒组成,这些颗粒被规则的无颗粒间隔彼此分隔开。