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70岁及以上患者在不使用体外循环情况下的心肌血运重建

Myocardial Revascularization in Patients 70 Years of Age and Older Without the Use of Extracorporeal Circulation.

作者信息

Buffolo Enio, Summo Henrique, Aguiar Luciano F., Teles Carlos Alberto, Branco João Nelson R.

机构信息

Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil.

出版信息

Am J Geriatr Cardiol. 1997 Jan;6(1):7-15.

Abstract

Myocardial revascularization in elderly patients (i.e., over 70 years of age) is associated with higher incidence of morbidity and mortality compared with younger patients. We herein report our experience on myocardial revascularization in the elderly comparing the results between 2 groups; one operated on with the aid of cardiopulmonary bypass and the other group in whom extracorporeal circulation was not used. The records of 265 elderly patients ( at or above 70 yrs) undergoing myocardial revascularization were prospectively analyzed between January 1994 and December 1995. Mean age was 74 Â+/- 6 years (range 70-95 yrs), with 83 (31.3%) females and 182 (68.7%) males. The following were the preoperative diagnoses: chronic ischemia and angina (186 patients), reoperation (28 patients), unstable angina (26 patients), failed angioplasty (13 patients), post-thrombolytic therapy (7 patients), cardiogenic shock (2 patients), evolving myocardial infarction (2 patients), and aortic dissection (1 patient). Extracorporeal circulation was used in 204 (76.9%) patients (Group I) and no extracorporeal circulation was used in 61 (23.1%) patients (Group II). The overall mortality was 6.4%, with 7.8% (16/204) in Group I and 1.6% (1/61) in Group II. Hospital stay was 11.4 days in Group I and 7.1 in Group II. Transfusion requirements were 1.4 and 0.6 units for Groups I and II, respectively. The use of extracorporeal circulation in the elderly is a major cause of morbidity and mortality following myocardial revascularization. Whenever possible, myocardial revascularization in the elderly should be performed without the use of extracorporeal circulation.

摘要

与年轻患者相比,老年患者(即70岁以上)的心肌血运重建术伴随着更高的发病率和死亡率。在此,我们报告老年患者心肌血运重建术的经验,比较两组的结果;一组在体外循环辅助下进行手术,另一组未使用体外循环。对1994年1月至1995年12月期间接受心肌血运重建术的265例老年患者(70岁及以上)的记录进行了前瞻性分析。平均年龄为74±6岁(范围70 - 95岁),其中女性83例(31.3%),男性182例(68.7%)。术前诊断如下:慢性缺血和心绞痛(186例患者)、再次手术(28例患者)、不稳定型心绞痛(26例患者)、血管成形术失败(13例患者)、溶栓治疗后(7例患者)、心源性休克(2例患者)、进展性心肌梗死(2例患者)和主动脉夹层(1例患者)。204例(76.9%)患者(第一组)使用了体外循环,61例(23.1%)患者(第二组)未使用体外循环。总体死亡率为6.4%,第一组为7.8%(16/204),第二组为1.6%(1/61)。第一组的住院时间为11.4天,第二组为7.1天。第一组和第二组的输血需求量分别为1.4单位和0.6单位。老年患者使用体外循环是心肌血运重建术后发病和死亡的主要原因。只要有可能,老年患者的心肌血运重建术应在不使用体外循环的情况下进行。

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