Otal P, Mezghani S, Hassissene S, Maleux G, Colombier D, Rousseau H, Joffre F
Service Central de Radiologie, CHU Rangueil, 1, Avenue Jean Poulhes, 31403 Toulouse, France.
Eur Radiol. 2001;11(6):940-5. doi: 10.1007/s003300000698.
The aim of this study was to describe the radiological appearance of retroperitoneal ganglioneuroma. We retrospectively reviewed seven cases of histologically proven retroperitoneal ganglioneuroma. Ultrasound and enhanced CT were obtained in all cases, and MRI in three cases. The masses were well-circumscribed, ranged in size from 5 x 3 x 3 to 10 x 6 x 4 cm. In three cases close relationships between the tumor mass and major blood vessels were noted, resulting in vessel displacement or surrounding, but without compression or occlusion. On ultrasound examination the tumor showed a heterogeneous solid echostructure. Non-enhanced CT showed homogeneous or mildly heterogeneous low attenuation, and a punctate calcification was seen in one case. Contrast uptake was absent (n = 1) or delayed (n = 6). Progressive but incomplete enhancement was observed in three cases. On MRI, T2-weighted images showed a high signal intensity. Dynamic studies depicted the same enhancement pattern as described on CT. Ganglioneuroma is a rare tumor which should nevertheless be included in differential diagnosis of retroperitoneal masses when presenting as a well-delimited tumor with possible tendency to surround or displace major blood vessels, low density on non-enhanced CT, and delayed progressive enhancement on CT and MRI.
本研究的目的是描述腹膜后神经节细胞瘤的影像学表现。我们回顾性分析了7例经组织学证实的腹膜后神经节细胞瘤。所有病例均行超声及增强CT检查,3例还进行了MRI检查。肿块边界清晰,大小范围为5×3×3至10×6×4厘米。3例可见肿瘤肿块与主要血管关系密切,导致血管移位或被包绕,但无压迫或阻塞。超声检查显示肿瘤呈不均匀实性回声结构。平扫CT显示均匀或轻度不均匀低密度,1例可见点状钙化。1例无强化,6例呈延迟强化。3例观察到渐进性但不完全强化。在MRI上,T2加权像显示高信号强度。动态研究显示与CT描述的强化模式相同。神经节细胞瘤是一种罕见肿瘤,当表现为边界清晰的肿瘤,可能有包绕或移位主要血管的倾向、平扫CT低密度以及CT和MRI延迟渐进性强化时,仍应纳入腹膜后肿块的鉴别诊断。