Ketley C E, Lennon M A
Department of Clinical Dental Sciences, The University of Liverpool School of Dentistry, Liverpool, UK.
Caries Res. 2001 Jul-Aug;35(4):252-7. doi: 10.1159/000047466.
Twenty-four-hour urine samples were collected from each of thirteen 5- to 6-year-old children both under customary conditions of fluoride intake (i.e. usual diet including milk containing 0.5 mg fluoride and usual oral hygiene procedures with fluoride toothpaste) and during a 4-day study period in which their customary fluoride intake was replaced with standard fluoride doses. The 24-hour fluoride excretion under customary conditions of fluoride intake was 0.30 mg and in response to fluoride doses in the range of 0.5-2.0 mg it was in the range 0.26-0.61 mg. Using data obtained during the study period for all subjects combined, the fluoride intake from all sources under customary conditions was estimated as 0.76 mg, representing a fractional fluoride excretion of 39%. It is concluded that these children are possibly receiving suboptimal amounts of fluoride.
从13名5至6岁儿童中分别采集24小时尿液样本，一次是在氟摄入量的常规条件下（即包括含0.5毫克氟的牛奶的日常饮食以及使用含氟牙膏的日常口腔卫生程序），另一次是在为期4天的研究期间，在此期间他们的常规氟摄入量被标准氟剂量所取代。在氟摄入量的常规条件下，24小时氟排泄量为0.30毫克，而在0.5 - 2.0毫克范围内的氟剂量作用下，排泄量在0.26 - 0.61毫克范围内。综合所有受试者在研究期间获得的数据，常规条件下所有来源的氟摄入量估计为0.76毫克，氟排泄分数为39%。结论是这些儿童可能摄入了次优量的氟。
