Nakajima H, Nakagomi T, Kamisawa T, Sakaki N, Muramoto K, Mikami T, Nara H, Nakagomi O
Lancet. 2001 Jun 16;357(9272):1950. doi: 10.1016/S0140-6736(00)05086-8.
We investigated the aetiological role of group A rotavirus in adults with acute diarrhoea in a 4-year prospective study. Of 683 patients with acute diarrhoea, 97 (14%) shed rotavirus as a sole agent, whereas six (5%) of 115 patients without diarrhoea shed rotavirus. Half of patients with rotavirus diarrhoea required admission to hospital. Unlike rotavirus diarrhoea in children, the occurrence of rotavirus-positive cases did not show a significant winter seasonality. Rotavirus infection should be included in the differential diagnosis of diarrhoeal diseases in adults.
我们在一项为期4年的前瞻性研究中,调查了A组轮状病毒在成人急性腹泻中的病因学作用。在683例急性腹泻患者中,97例(14%)排出的轮状病毒是唯一病原体,而在115例无腹泻患者中,有6例(5%)排出轮状病毒。半数轮状病毒腹泻患者需要住院治疗。与儿童轮状病毒腹泻不同,轮状病毒阳性病例的发生没有明显的冬季季节性。成人腹泻病的鉴别诊断应包括轮状病毒感染。