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明尼苏达州儿童创伤性脑损伤的流行病学

The epidemiology of pediatric traumatic brain injury in Minnesota.

作者信息

Reid S R, Roesler J S, Gaichas A M, Tsai A K

机构信息

Pediatric Emergency Medicine, Children's Hospitals and Clinics, 345 N Smith Ave, St Paul, MN 55102, USA.

出版信息

Arch Pediatr Adolesc Med. 2001 Jul;155(7):784-9. doi: 10.1001/archpedi.155.7.784.

DOI:10.1001/archpedi.155.7.784
PMID:11434844
Abstract

OBJECTIVES

To determine the epidemiology of pediatric traumatic brain injury (TBI) in a midwestern state and to examine differences between metropolitan and nonmetropolitan residents.

DESIGN

Population-based case series.

PARTICIPANTS

Patients aged 0-19 years sustaining TBI in 1993 that resulted in hospitalization or death.

INTERVENTIONS

None.

MAIN OUTCOME MEASURES

Incidence, mortality and case-fatality rates, length of hospital stay, discharge status, and Glasgow Outcome Scale score.

RESULTS

Nine hundred seventy-seven patients met inclusion criteria. Incidence, mortality, and case-fatality rates were 73.5 per 100 000, 9.3 per 100 000, and 12.8 per 100, respectively. Higher median household incomes and percentages of adult high-school graduates in a patient's census block group correlated with lower incidence. Median length of stay was 2 days. Of those included in the study, 720 patients (74%) were discharged home with self-care. Three hundred fifty-seven patients met criteria for severe TBI; 346 (97%) were assigned Glasgow Outcome Scale scores, of which 161 (47%) had disabilities or died. Severe TBI was associated with nonmetropolitan residence, higher median household income, and certain injury mechanisms. Incidence was similar for metropolitan and nonmetropolitan residents. Median head-region Abbreviated Injury Score, Injury Severity Score, and mortality and case-fatality rates were higher for nonmetropolitan residents.

CONCLUSIONS

This study reports the lowest incidence of pediatric TBI that results in death or hospitalization to date. One half of severely injured patients suffered poor outcomes. A greater proportion of nonmetropolitan than metropolitan residents suffered severe TBI and had higher mortality and case-fatality rates.

摘要

目的

确定美国中西部某州儿童创伤性脑损伤(TBI)的流行病学特征,并研究大城市和非大城市居民之间的差异。

设计

基于人群的病例系列研究。

参与者

1993年发生TBI并导致住院或死亡的0至19岁患者。

干预措施

无。

主要观察指标

发病率、死亡率和病死率、住院时间、出院状态以及格拉斯哥预后评分。

结果

977例患者符合纳入标准。发病率、死亡率和病死率分别为每10万人73.5例、每10万人9.3例和每100例12.8例。患者普查街区组中较高的家庭收入中位数和成人高中毕业生百分比与较低的发病率相关。中位住院时间为2天。在纳入研究的患者中,720例(74%)出院回家并能自理。357例患者符合重度TBI标准;346例(97%)获得格拉斯哥预后评分,其中161例(47%)有残疾或死亡。重度TBI与非大城市居住、较高的家庭收入中位数和某些损伤机制有关。大城市和非大城市居民的发病率相似。非大城市居民的头部区域简明损伤评分、损伤严重程度评分中位数以及死亡率和病死率较高。

结论

本研究报告了迄今为止导致死亡或住院的儿童TBI的最低发病率。一半的重伤患者预后不良。非大城市居民中重度TBI患者的比例高于大城市居民,且死亡率和病死率更高。

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