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患急性腹膜炎牛的血浆蛋白变化

Plasma protein alterations in cattle suffering from acute peritonitis.

作者信息

Miclaus I, Brummerstedt E

出版信息

Nord Vet Med. 1975 Apr;27(4):203-7.

PMID:1144015
Abstract

Modification of the normal plasma protein picture has been studied in plasma samples from cows suffering from spontaneously arisen (17 cases) or experimentally induced acute peritonitis (5 cases) using polyacrylamide electrophoresis. Considerable differences were found in the postalbumin region during peritonitis. One protein component increased in size, while another disappeared. Two weak components in normal samples were replaced by four discrete protein bands. These modifications were not detected in any of 10 plasma samples from cows suffering from other diseases than peritonitis or in any of 35 samples from clinically healthy animals. The modifications were visible 12-16 h after injection of the provoking agent and were remarkably alike from one case to the next.

摘要

利用聚丙烯酰胺电泳,对患有自发性(17例)或实验性诱导急性腹膜炎(5例)的奶牛血浆样本中正常血浆蛋白图谱的改变进行了研究。在腹膜炎期间,在后白蛋白区域发现了相当大的差异。一种蛋白质成分大小增加,而另一种消失。正常样本中的两个弱成分被四条离散的蛋白带所取代。在患有腹膜炎以外其他疾病的奶牛的10份血浆样本或35份临床健康动物的样本中,均未检测到这些改变。在注射激发剂后12 - 16小时,这些改变可见,并且在不同病例之间非常相似。

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