[皱褶青霉素A和B——来自皱褶青霉和鱼青霉真菌的二酮哌嗪生物碱]

[Rugulosuvines A and B--diketopiperazine alkaloids from Penicillium rugulosum and Penicillium piscarium fungi].

作者信息

Kozlovskiĭ A G, Adanin V M, Dahse H M, Grafe U

机构信息

G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, prosp. Nauki 5, Pushchino, 142290 Russia.

出版信息

Prikl Biokhim Mikrobiol. 2001 May-Jun;37(3):292-6.

PMID:11443897

Abstract

Two diketopiperazine alkaloids, rugulosuvines A and B (tryptophan and phenylalanine are precursors), were isolated and purified from the culture liquid of Penicillium rugulosum VKM F-352 and Penicillium piscarium VKM F-325 fungi. Physical and physicochemical studies showed the absolute structure of rugulosuvine A. The absolute structure of rugulosuvine B was demonstrated to be similar to that of rugulosuvine A.

摘要

从皱褶青霉VKM F-352和鱼青霉VKM F-325真菌的培养液中分离并纯化出两种二酮哌嗪生物碱，皱褶苏氨酸A和B（色氨酸和苯丙氨酸是前体）。物理和物理化学研究表明了皱褶苏氨酸A的绝对结构。已证明皱褶苏氨酸B的绝对结构与皱褶苏氨酸A相似。