Brockow T, Dillner A, Franke A, Resch K L
Research Institute for Spa Therapies and Health Resort Science, Bad Elster, Germany.
Complement Ther Med. 2001 Jun;9(2):68-76. doi: 10.1054/ctim.2001.0434.
To evaluate the analgesic effectiveness of subcutaneous carbon-dioxide insufflations in addition to standard physical treatment in patients with non-specific neck or low back pain.
A pragmatic, randomized controlled trial.
Rehabilitation hospital inpatients.
Patients received either subcutaneous carbon-dioxide insufflations (10 treatments) and standard physical treatment or standard physical treatment only.
Affective pain perception (42-point scale), sensory pain perception (30-point scale), pain intensity (100 mm visual analogue scale).
Between-groups differences were -2.2 [95% CI -5.2; +0.9] (affective pain perception), -1.2 [-3, 0; + 0.7] (sensory pain perception), and -6.5 [-14; +1.0] (pain intensity) respectively in favour of subcutaneous carbon-dioxide insufflations.
Subcutaneous carbon-dioxide insufflations do not seem to be a worthwhile adjunct in the given setting of inpatient rehabilitation. Trials in a monotherapeutic setting, which aim more at the efficacy of subcutaneous carbon-dioxide insufflations, might help to solve this issue.
评估在标准物理治疗基础上,皮下注射二氧化碳对非特异性颈部或下背部疼痛患者的镇痛效果。
一项实用的随机对照试验。
康复医院住院部。
患者接受皮下注射二氧化碳(10次治疗)加标准物理治疗或仅接受标准物理治疗。
情感性疼痛感知(42分制)、感觉性疼痛感知(30分制)、疼痛强度(100毫米视觉模拟量表)。
组间差异分别为-2.2 [95%置信区间-5.2;+0.9](情感性疼痛感知)、-1.2 [-3.0;+0.7](感觉性疼痛感知)和-6.5 [-14;+1.0](疼痛强度),均支持皮下注射二氧化碳。
在住院康复环境中,皮下注射二氧化碳似乎并非一项值得采用的辅助治疗方法。在单一治疗环境下开展的试验,若更多关注皮下注射二氧化碳的疗效,可能有助于解决这一问题。