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皮下二氧化碳注入作为非特异性颈部或下背部疼痛患者辅助治疗的镇痛效果。

Analgesic effectiveness of subcutaneous carbon-dioxide insufflations as an adjunct treatment in patients with non-specific neck or low back pain.

作者信息

Brockow T, Dillner A, Franke A, Resch K L

机构信息

Research Institute for Spa Therapies and Health Resort Science, Bad Elster, Germany.

出版信息

Complement Ther Med. 2001 Jun;9(2):68-76. doi: 10.1054/ctim.2001.0434.

Abstract

OBJECTIVES

To evaluate the analgesic effectiveness of subcutaneous carbon-dioxide insufflations in addition to standard physical treatment in patients with non-specific neck or low back pain.

DESIGN

A pragmatic, randomized controlled trial.

SETTING

Rehabilitation hospital inpatients.

INTERVENTIONS

Patients received either subcutaneous carbon-dioxide insufflations (10 treatments) and standard physical treatment or standard physical treatment only.

OUTCOME MEASURES

Affective pain perception (42-point scale), sensory pain perception (30-point scale), pain intensity (100 mm visual analogue scale).

RESULTS

Between-groups differences were -2.2 [95% CI -5.2; +0.9] (affective pain perception), -1.2 [-3, 0; + 0.7] (sensory pain perception), and -6.5 [-14; +1.0] (pain intensity) respectively in favour of subcutaneous carbon-dioxide insufflations.

CONCLUSIONS

Subcutaneous carbon-dioxide insufflations do not seem to be a worthwhile adjunct in the given setting of inpatient rehabilitation. Trials in a monotherapeutic setting, which aim more at the efficacy of subcutaneous carbon-dioxide insufflations, might help to solve this issue.

摘要

目的

评估在标准物理治疗基础上,皮下注射二氧化碳对非特异性颈部或下背部疼痛患者的镇痛效果。

设计

一项实用的随机对照试验。

地点

康复医院住院部。

干预措施

患者接受皮下注射二氧化碳(10次治疗)加标准物理治疗或仅接受标准物理治疗。

观察指标

情感性疼痛感知(42分制)、感觉性疼痛感知(30分制)、疼痛强度(100毫米视觉模拟量表)。

结果

组间差异分别为-2.2 [95%置信区间-5.2;+0.9](情感性疼痛感知)、-1.2 [-3.0;+0.7](感觉性疼痛感知)和-6.5 [-14;+1.0](疼痛强度),均支持皮下注射二氧化碳。

结论

在住院康复环境中,皮下注射二氧化碳似乎并非一项值得采用的辅助治疗方法。在单一治疗环境下开展的试验,若更多关注皮下注射二氧化碳的疗效,可能有助于解决这一问题。

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