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图像引导声学治疗

Image-guided acoustic therapy.

作者信息

Vaezy S, Andrew M, Kaczkowski P, Crum L

机构信息

Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington 98105-6698, USA.

出版信息

Annu Rev Biomed Eng. 2001;3:375-90. doi: 10.1146/annurev.bioeng.3.1.375.

Abstract

The potential role of therapeutic ultrasound in medicine is promising. Currently, medical devices are being developed that utilize high-intensity focused ultrasound as a noninvasive method to treat tumors and to stop bleeding (hemostasis). The primary advantage of ultrasound that lends the technique so readily to use in noninvasive therapy is its ability to penetrate deep into the body and deliver to a specific site thermal or mechanical energy with submillimeter accuracy. Realizing the full potential of acoustic therapy, however, requires precise targeting and monitoring. Fortunately, several imaging modalities can be utilized for this purpose, thus leading to the concept of image-guided acoustic therapy. This article presents a review of high-intensity focused ultrasound therapy, including its mechanisms of action, the imaging modalities used for guidance and monitoring, some current applications, and the requirements and technology associated with this exciting and promising field.

摘要

治疗性超声在医学中的潜在作用前景广阔。目前,正在开发利用高强度聚焦超声作为一种非侵入性方法来治疗肿瘤和止血的医疗设备。超声技术如此易于用于非侵入性治疗的主要优势在于其能够深入人体并以亚毫米精度将热能或机械能传递到特定部位。然而,要充分发挥声学治疗的潜力,需要精确的靶向和监测。幸运的是,有几种成像方式可用于此目的,从而产生了图像引导声学治疗的概念。本文对高强度聚焦超声治疗进行了综述,包括其作用机制、用于引导和监测的成像方式、一些当前的应用以及与这个令人兴奋且前景广阔的领域相关的要求和技术。

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