脑室内注射去甲肾上腺素期间的品系差异：受体敏感性的可能作用。
Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity.
作者信息
Segal D S, Geyer M A, Weiner B E
出版信息
Science. 1975 Jul 25;189(4199):301-3. doi: 10.1126/science.1145205.
PMID:1145205
Abstract
Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.
摘要
先前已证明两种大鼠品系在行为活动、脑区酪氨酸羟化酶活性以及去甲肾上腺素引发的3',5'-环磷酸腺苷积累方面存在差异，在脑室内注入去甲肾上腺素期间，它们表现出不同的行为反应性。结果根据不同的儿茶酚胺受体敏感性进行解释。
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