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脑室内注射去甲肾上腺素期间的品系差异：受体敏感性的可能作用。

Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity.

作者信息

Segal D S, Geyer M A, Weiner B E

出版信息

Science. 1975 Jul 25;189(4199):301-3. doi: 10.1126/science.1145205.

DOI:10.1126/science.1145205
PMID:1145205
Abstract

Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.

摘要

先前已证明两种大鼠品系在行为活动、脑区酪氨酸羟化酶活性以及去甲肾上腺素引发的3',5'-环磷酸腺苷积累方面存在差异，在脑室内注入去甲肾上腺素期间，它们表现出不同的行为反应性。结果根据不同的儿茶酚胺受体敏感性进行解释。

相似文献

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Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity.脑室内注射去甲肾上腺素期间的品系差异：受体敏感性的可能作用。
Science. 1975 Jul 25;189(4199):301-3. doi: 10.1126/science.1145205.
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Increased fixed-ratio performance and differential d- and l-amphetamine action following norepinephrine depletion by intraventricular 6-hydroxydopamine.经脑室内注射6-羟基多巴胺使去甲肾上腺素耗竭后，固定比率行为表现增强以及d-和l-苯丙胺作用出现差异。
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Effect of intraventricular infusion of dopamine and norepinephrine on motor activity.脑室内注入多巴胺和去甲肾上腺素对运动活性的影响。
Physiol Behav. 1972 Apr;8(4):653-8. doi: 10.1016/0031-9384(72)90090-x.

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