苯丙胺类药物所致急性心肌梗死：一例报告并文献复习

Acute myocardial infarction caused by amphetamines: a case report and review of the literature.

作者信息

Costa G M, Pizzi C, Bresciani B, Tumscitz C, Gentile M, Bugiardini R

机构信息

Department of Internal Medicine, Cardioangiology and Hepatology, Imola Hospital, Universitv of Bologna, Italy.

出版信息

Ital Heart J. 2001 Jun;2(6):478-80.

PMID:11453588

Abstract

Cardiotoxicity manifesting as myocardial ischemia is not generally recognized as a side effect of amphetamine use or abuse. However, at least 9 cases have been reported since 1987. In this report a case of acute myocardial infarction due to oral amphetamine therapy is presented. The patient was treated with thrombolytic therapy but there were no signs of reperfusion. His coronary cine-angiograms were normal. The literature regarding amphetamine use or abuse is also reviewed, and the possible mechanisms of this pathology are analyzed.

摘要

表现为心肌缺血的心脏毒性通常不被认为是使用或滥用苯丙胺的副作用。然而，自1987年以来至少已报告9例。本报告介绍了1例因口服苯丙胺治疗导致急性心肌梗死的病例。该患者接受了溶栓治疗，但没有再灌注迹象。其冠状动脉血管造影正常。本文还回顾了有关苯丙胺使用或滥用的文献，并分析了这种病理情况的可能机制。