De Geronimo F, Glacet-Bernard A, Coscas G, Soubrane G
University Eye Clinic of Créteil, France.
Eur J Ophthalmol. 2001 Apr-Jun;11(2):145-9. doi: 10.1177/112067210101100207.
To evaluate quantitatively the effect of grid laser photocoagulation in macular edema due to central and branch retinal vein occlusion, using the retinal thickness analyzer.
Five patients with cystoid and non-cystoid macular edema were studied before and after argon grid laser treatment. All were examined clinically, with fluorescein angiography, and measurement of retinal thickness. Macular thickness was correlated to visual acuity measured on the ETDRS chart.
Laser-slit images obtained with the retinal thickness analyzer in patients with macular edema disclosed discrete intraretinal changes after photocoagulation. Biomicroscopy and fluorescein angiography were insensitive to these small changes in the retinal thickness. No patient had any change in visual acuity after three months, but the retinal thickness was greater at this interval. The retinal thickening may be explained by a postoperative inflammatory response or by altered retinal blood flow or, in two of the eyes, by the effect of combined peripheral photocoagulation.
The retinal thickness analyzer offers a refined tool for the diagnosis of subclinical changes of macular edema in retinal vein occlusion and is therefore also useful for assessing the effects of treatment.
使用视网膜厚度分析仪定量评估格栅样激光光凝术对视网膜中央静脉阻塞和视网膜分支静脉阻塞所致黄斑水肿的疗效。
对5例患有囊样和非囊样黄斑水肿的患者在氩激光格栅样光凝治疗前后进行研究。所有患者均接受临床检查、荧光素血管造影以及视网膜厚度测量。黄斑厚度与ETDRS视力表所测视力相关。
黄斑水肿患者经视网膜厚度分析仪获得的激光裂隙图像显示光凝后视网膜内有离散性改变。生物显微镜检查和荧光素血管造影对视网膜厚度的这些微小变化不敏感。三个月后所有患者视力均无变化，但此时视网膜厚度增加。视网膜增厚可能是由于术后炎症反应、视网膜血流改变，或者在其中两只眼中是由于联合周边光凝的作用。
视网膜厚度分析仪为诊断视网膜静脉阻塞黄斑水肿的亚临床变化提供了一种精确工具，因此也有助于评估治疗效果。
