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输尿管镜检查的并发症:预测因素分析

Complications of ureteroscopy: analysis of predictive factors.

作者信息

Schuster T G, Hollenbeck B K, Faerber G J, Wolf J S

机构信息

Section of Urology, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Urol. 2001 Aug;166(2):538-40. doi: 10.1016/s0022-5347(05)65978-2.

Abstract

PURPOSE

Although overall and major complication rates of 10% to 20% and 0% to 6%, respectively, have been observed in large series of ureteroscopy, to our knowledge no systemic analysis to determine factors predictive of these complications has been reported.

MATERIALS AND METHODS

We retrospectively reviewed all ureteroscopies performed at our institution for calculous disease from January 1997 through September 1999. A total of 322 procedures were performed by 5 attending surgeons. Intraoperative and immediate postoperative complications were identified. Bivariate and multivariate analysis was performed to identify associated factors with ureteral perforation and postoperative complications as the dependent variables.

RESULTS

Bivariate analysis showed a significant association of ureteral perforation with increased operative time (p = 0.0001). In addition, we noted a significant association of postoperative complications with stones in the kidney (p = 0.0004), operative time (p = 0.05) and decreased surgeon experience (p = 0.0035) as well as a trend toward significance for the type of ureteroscope used (p = 0.0609). In multivariate logistic regression models ureteral perforation remained highly associated with operative time (p = 0.0005) when controlling for the other factors. Similarly decreased surgeon experience and a stone in the kidney were predictive of postoperative complications when controlling for the other factors (p = 0.004).

CONCLUSIONS

Longer duration of the ureteroscopic procedure is strongly associated with ureteral perforation. The likelihood of immediate postoperative complications is greater when renal calculi are treated and less when the surgeon is more experienced.

摘要

目的

尽管在大量输尿管镜检查系列研究中分别观察到总体并发症发生率为10%至20%,主要并发症发生率为0%至6%,但据我们所知,尚未有系统性分析来确定这些并发症的预测因素。

材料与方法

我们回顾性分析了1997年1月至1999年9月在本机构进行的所有因结石疾病而实施的输尿管镜检查。共有5位主治医生实施了322例手术。确定术中及术后即刻并发症。以输尿管穿孔和术后并发症为因变量进行双变量和多变量分析,以确定相关因素。

结果

双变量分析显示输尿管穿孔与手术时间延长显著相关(p = 0.0001)。此外,我们注意到术后并发症与肾结石(p = 0.0004)、手术时间(p = 0.05)、医生经验减少(p = 0.0035)以及所用输尿管镜类型存在显著关联趋势(p = 0.0609)。在多变量逻辑回归模型中,在控制其他因素时,输尿管穿孔仍与手术时间高度相关(p = 0.0005)。同样,在控制其他因素时,医生经验减少和肾结石可预测术后并发症(p = 0.004)。

结论

输尿管镜手术时间延长与输尿管穿孔密切相关。治疗肾结石时术后即刻发生并发症的可能性更大,而医生经验越丰富,术后即刻发生并发症的可能性越小。

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