Sogani P C, Ray B, Whitmore W F
Urology. 1975 Aug;6(2):164-6. doi: 10.1016/0090-4295(75)90704-9.
Twenty-six patients with advanced prostatic carcinoma refractory to conventional endocrine treatment were treated with a new oral nonsteriodal antiandrogen, flutamide. There were 6 responders and 20 failures. No serious toxicity attributable to flutamide was observed.
26例对常规内分泌治疗无效的晚期前列腺癌患者接受了一种新型口服非甾体抗雄激素药物氟他胺的治疗。有6例有反应,20例无效。未观察到因氟他胺引起的严重毒性反应。