Tran H S, Puc M M, Tran J L, Del Rossi A J, Hewitt C W
Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper Health System/University Medical Center, Camden, New Jersey, USA.
Lab Anim. 2001 Jul;35(3):249-52. doi: 10.1258/0023677011911705.
Endotracheal intubation in rabbits is a formidable task and has led to the devising of a new endoscopic method. Sixty New Zealand White rabbits (2.0-3.5 kg) underwent experimental left thoracotomy requiring mechanical ventilation. After anaesthetic induction was achieved, the animal was placed in a supine position. A rigid 30 degrees endoscope was passed through a 4.5 mm endotracheal tube (ET) and then used to advance, under direct vision, through the oropharynx and vocal cords. Once passing the vocal cords, the ET was advanced into the trachea as the endoscope was withdrawn. All animals were successfully intubated within 30 s to 2 min and then ventilated. No complications or deaths occurred during or after intubation, or postoperatively. No instances of oesophageal intubation occurred. All animals survived long-term. Thirty animals underwent necropsy at 10 days and, 30 at 30 days, with no postoperative evidence of orotracheal injury. We have established a new method of endotracheal intubation in rabbits. It is reliable, effective, non-traumatic, safe, and expeditious.
对兔子进行气管插管是一项艰巨的任务,因此人们设计出了一种新的内镜方法。六十只新西兰白兔(体重2.0 - 3.5千克)接受了需要机械通气的实验性左胸切开术。麻醉诱导成功后,将动物置于仰卧位。将一根30度的硬质内窥镜通过一根4.5毫米的气管导管,然后在内窥镜直视下推进,穿过口咽和声门。一旦通过声门,在内窥镜撤回时将气管导管推进气管。所有动物均在30秒至2分钟内成功插管,然后进行通气。插管期间、插管后或术后均未发生并发症或死亡。未发生食管插管情况。所有动物均长期存活。30只动物在10天时进行了尸检,30只在30天时进行了尸检,术后均无口气管损伤的证据。我们建立了一种新的兔子气管插管方法。它可靠、有效、无创、安全且迅速。