Hepcidin: a putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease.
作者信息
Fleming R E, Sly W S
机构信息
Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO 63014, USA.
出版信息
Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8160-2. doi: 10.1073/pnas.161296298.
Abstract
摘要
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本文引用的文献
1
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice.上游刺激因子2（USF2）基因敲除小鼠中缺乏铁调素基因表达及严重的组织铁过载
Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8780-5. doi: 10.1073/pnas.151179498. Epub 2001 Jul 10.
2
Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload.缺铁和铁过载状态下十二指肠铁转运蛋白二价金属转运体1和铁转运蛋白1的表达
Gastroenterology. 2001 May;120(6):1412-9. doi: 10.1053/gast.2001.24033.
3
New mutations inactivating transferrin receptor 2 in hemochromatosis type 3.3型血色素沉着症中使转铁蛋白受体2失活的新突变。
Blood. 2001 May 1;97(9):2555-60. doi: 10.1182/blood.v97.9.2555.
4
An iron-regulated ferric reductase associated with the absorption of dietary iron.一种与膳食铁吸收相关的铁调节性三价铁还原酶。
Science. 2001 Mar 2;291(5509):1755-9. doi: 10.1126/science.1057206. Epub 2001 Feb 1.
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Hemochromatosis: diagnosis and management.血色素沉着症：诊断与管理
Gastroenterology. 2001 Feb;120(3):718-25. doi: 10.1053/gast.2001.21913.
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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload.一种新的小鼠肝脏特异性基因，编码一种与人抗菌肽铁调素同源的蛋白质，在铁过载期间过度表达。
J Biol Chem. 2001 Mar 16;276(11):7811-9. doi: 10.1074/jbc.M008923200. Epub 2000 Dec 11.
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Hepcidin, a urinary antimicrobial peptide synthesized in the liver.铁调素，一种在肝脏中合成的尿抗菌肽。
J Biol Chem. 2001 Mar 16;276(11):7806-10. doi: 10.1074/jbc.M008922200. Epub 2000 Dec 11.
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Iron homeostasis: new tales from the crypt.铁稳态：来自隐秘之处的新故事。
Blood. 2000 Dec 15;96(13):4020-7.
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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity.LEAP-1是一种新型的高度二硫键连接的人肽，具有抗菌活性。
FEBS Lett. 2000 Sep 1;480(2-3):147-50. doi: 10.1016/s0014-5793(00)01920-7.
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A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.一种新的十二指肠铁调节转运蛋白IREG1，参与铁从基底外侧向循环系统的转运。
Mol Cell. 2000 Feb;5(2):299-309. doi: 10.1016/s1097-2765(00)80425-6.
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