Thumboo J, Chew L H, Soh C H
The Departments of Rheumatology and Immunology, Tan Tock Seng Hospital, Singapore.
Osteoarthritis Cartilage. 2001 Jul;9(5):440-6. doi: 10.1053/joca.2000.0410.
To assess the reliability and validity of the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) as an outcome measure in Asian patients with knee or hip osteoarthritis (OA) in Singapore.
The WOMAC was administered twice 7 days apart to 66 consecutive English-speaking Chinese, Malay or Indian inpatients and outpatients with knee or hip OA seen at a tertiary referral centre through a structured interview, which also assessed demographic and other characteristics. Internal consistency was assessed using Cronbach's alpha, reliability using Spearman's correlations, intraclass correlations and repeatability coefficients, and relationships between WOMAC domains and known determinants of function using Spearman's correlations and the Mann-Whitney U-test.
The WOMAC showed good internal consistency (alpha=0.70 to 0.93) and good reliability, with intraclass correlations of 0.83 to 0.90 and mean test-retest score differences of 0.02 to 0.13 points (possible range 4 points). Results of Likert scoring assessment supported the validity of the WOMAC when interpreted in the context of the close association between pain and physical function. Eight of nine a priori hypotheses relating WOMAC Pain and Physical Function scores to known determinants of function were present, supporting construct validity of this scale.
The WOMAC is a valid and reliable outcome measure in Asian patients with OA in Singapore.
评估西安大略和麦克马斯特大学骨关节炎指数（WOMAC）作为新加坡亚洲膝关节或髋关节骨关节炎（OA）患者结局指标的可靠性和有效性。
通过结构化访谈对一家三级转诊中心连续收治的66名说英语的华裔、马来裔或印度裔膝关节或髋关节OA住院患者和门诊患者进行WOMAC评估，间隔7天进行两次，访谈还评估了人口统计学和其他特征。使用Cronbach's alpha评估内部一致性，使用Spearman相关性、组内相关性和重复性系数评估可靠性，并使用Spearman相关性和Mann-Whitney U检验评估WOMAC各领域与已知功能决定因素之间的关系。
WOMAC显示出良好的内部一致性（α=0.70至0.93）和良好的可靠性，组内相关性为0.83至0.90，重测分数平均差异为0.02至0.13分（可能范围为4分）。Likert评分评估结果支持在疼痛与身体功能密切相关的背景下对WOMAC进行有效性解释。在将WOMAC疼痛和身体功能评分与已知功能决定因素相关的九个先验假设中，有八个成立，支持了该量表的结构效度。
WOMAC是新加坡亚洲OA患者有效且可靠的结局指标。
