Safavi K, Nakayama T A
Department of Endodontology, School of Dental Medicine, University of Connecticut Health Center, Farmington 06030-1715, USA.
J Endod. 2000 Nov;26(11):649-51. doi: 10.1097/00004770-200011000-00004.
The antimicrobial effects of aqueous preparations of calcium hydroxide have been demonstrated in the past. Calcium hydroxide, when dissolved in water, dissociates into hydroxide and calcium ions. The presence of hydroxide ions in a solution makes it antimicrobial. Recently it was shown that the use of glycerin as a mixing vehicle facilitates placement of calcium hydroxide in the root canals. The influence of nonaqueous mixing vehicles on the dissociation of calcium hydroxide is not clearly understood. In this study the conductivity of aqueous and nonaqueous solutions of calcium hydroxide was measured. The conductivity values for saturated solutions of calcium hydroxide in water was 7.3+/-3 mS/cm. The conductivity of calcium hydroxide in pure glycerin or propylene glycol was essentially zero. It was concluded that use of nonaqueous mixing vehicles may impede the effectiveness of calcium hydroxide as a root canal dressing.
过去已证实氢氧化钙水制剂具有抗菌作用。氢氧化钙溶于水时会解离成氢氧根离子和钙离子。溶液中氢氧根离子的存在使其具有抗菌性。最近有研究表明，使用甘油作为混合媒介有助于将氢氧化钙放置于根管中。目前尚不清楚非水混合媒介对氢氧化钙解离的影响。在本研究中，对氢氧化钙水溶液和非水溶液的电导率进行了测量。氢氧化钙在水中饱和溶液的电导率值为7.3±3 mS/cm。氢氧化钙在纯甘油或丙二醇中的电导率基本为零。研究得出结论，使用非水混合媒介可能会妨碍氢氧化钙作为根管敷料的有效性。
