Afkhami Farzaneh, Elahy Sadaf, Nahavandi Alireza Mahmoudi, Kharazifard Mohamad Javad, Sooratgar Aidin
Department of Endodontics, Faculty of Dentistry, Tehran University of Medical Sciences, International Campus, Tehran, Iran.
General Dentist, Private Practice, Tehran, Iran.
Restor Dent Endod. 2019 Feb 12;44(1):e10. doi: 10.5395/rde.2019.44.e10. eCollection 2019 Feb.
The objective of this study was to assess coronal discoloration induced by the following intracanal medicaments: calcium hydroxide (CH), a mixture of CH paste and chlorhexidine gel (CH/CHX), and triple antibiotic paste (3Mix).
Seventy extracted single-canal teeth were selected. Access cavities were prepared and each canal was instrumented with a rotary ProTaper system. The specimens were randomly assigned to CH, CH/CHX, and 3Mix paste experimental groups ( = 20 each) or a control group ( = 10). Each experimental group was randomly divided into 2 subgroups (A and B). In subgroup A, medicaments were only applied to the root canals, while in subgroup B, the root canals were completely filled with medicaments and a cotton pellet dipped in medicament was also placed in the pulp chamber. Spectrophotometric readings were obtained from the mid-buccal surface of the tooth crowns immediately after placing the medicaments (T1) and at 1 week (T2), 1 month (T3), and 3 months (T4) after filling. The ∆E was then calculated. Data were analyzed using 2-way analysis of variance (ANOVA), 3-way ANOVA, and the Scheffé test.
The greatest color change (ΔE) was observed at 3 months ( < 0.0001) and in 3Mix subgroup B ( = 0.0057). No significant color change occurred in the CH ( = 0.7865) or CH/CHX ( = 0.1367) groups over time, but the 3Mix group showed a significant ΔE ( = 0.0164).
Intracanal medicaments may induce tooth discoloration. Use of 3Mix must be short and it must be carefully applied only to the root canals; the access cavity should be thoroughly cleaned afterwards.
本研究的目的是评估以下根管内药物引起的冠部变色情况：氢氧化钙（CH）、CH糊剂与氯己定凝胶的混合物（CH/CHX）以及三联抗生素糊剂（3Mix）。
选取70颗拔除的单根管牙。制备开髓腔，每个根管使用旋转ProTaper系统进行预备。将标本随机分为CH、CH/CHX和3Mix糊剂实验组（每组n = 20）或对照组（n = 10）。每个实验组随机分为2个亚组（A和B）。在亚组A中，药物仅应用于根管；而在亚组B中，根管完全充满药物，并且在髓腔内还放置了浸有药物的棉球。在放置药物后立即（T1）以及充填后1周（T2）、1个月（T3）和3个月（T4）从牙冠的颊中面进行分光光度读数。然后计算ΔE。使用双向方差分析（ANOVA）、三向ANOVA和Scheffé检验对数据进行分析。
在3个月时观察到最大的颜色变化（ΔE）（P < 0.0001），并且在3Mix亚组B中（P = 0.0057）。随着时间的推移，CH组（P = 0.7865）或CH/CHX组（P = 0.1367）未发生显著的颜色变化，但3Mix组显示出显著的ΔE（P = 0.0164）。
根管内药物可能会导致牙齿变色。3Mix的使用时间必须短暂，并且必须仅小心地应用于根管；之后应彻底清洁开髓腔。
