Turk B Tugba, Sen Bilge Hakan, Ozturk Tansel
Division of Endodontology, School of Dentistry, Ege University, Izmir, Turkey.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Aug;108(2):297-301. doi: 10.1016/j.tripleo.2009.03.029.
The purpose of this in vitro study was to investigate antimicrobial activity of calcium hydroxide (CH) in combination with glycerin, chlorhexidine gluconate (CHX), cetrimide, or distilled water against Enterococcus faecalis and Candida albicans.
Standard holes in the cultivated agar plates were filled with one of the CH preparations and control agents. The zones of microbial inhibition were measured after incubation period.
The CH preparations with glycerin and CHX demonstrated more antifungal activity than CH preparations with cetrimide and distilled water. The CH-glycerin preparations had no effect against E. faecalis, and CH-CHX preparation was the most effective medication.
Antimicrobial activity of CH may change with the type of the vehicle and against different microorganisms. Enterococcus faecalis was more resistant than C. albicans to CH preparations.
本体外研究的目的是调查氢氧化钙（CH）与甘油、葡萄糖酸氯己定（CHX）、西曲溴铵或蒸馏水联合使用对粪肠球菌和白色念珠菌的抗菌活性。
在培养的琼脂平板上的标准孔中填充一种CH制剂和对照剂。培养期后测量微生物抑制圈。
含甘油和CHX的CH制剂比含西曲溴铵和蒸馏水的CH制剂表现出更强的抗真菌活性。CH-甘油制剂对粪肠球菌无效，CH-CHX制剂是最有效的药物。
CH的抗菌活性可能因载体类型和不同微生物而改变。粪肠球菌比白色念珠菌对CH制剂更具抗性。
