Harris M N, Roses D F, Culliford A T, Gumport S L
Ann Surg. 1975 Jul;182(1):86-91. doi: 10.1097/00000658-197507000-00016.
A series of 94 patients with cutaneous malignant melanoma of the head and neck region has been studied. Fifty-three of the patients had regional lymph node dissections performed and the results in 37 performed more than 5 years ago are presented. The policy of elective lymph node dissection for invasive melanoma of the head and neck is strongly endorsed, although not proven by the data presented in this limited series. Whenever possible, a total excisional biopsy should be performed to establish the diagnosis. It is recommended that all melanomas be classified by the method of Clark and Mihm and that the level of invasion also be determined. There is an appreciable error in the clinical evaluation of lymph nodes for metastases. In general, it is suggested that elective regional lymph node dissections be performed for invasive melanoma (levels III, IV and V). The literature pertaining to cutaneous melanoma of the head and neck has been reviewed and surgical and pathological problems peculiar to lesions of this region are emphasized.
对94例头颈部皮肤恶性黑色素瘤患者进行了研究。其中53例患者接受了区域淋巴结清扫术，本文呈现了37例5年多前进行手术的患者的结果。尽管本有限系列所呈现的数据尚未证实，但强烈支持对头颈部浸润性黑色素瘤进行选择性淋巴结清扫的策略。只要有可能，应进行完整切除活检以确立诊断。建议所有黑色素瘤均按照克拉克（Clark）和米姆（Mihm）的方法进行分类，并确定浸润深度。在临床评估淋巴结转移方面存在明显误差。一般而言，建议对浸润性黑色素瘤（III、IV和V级）进行选择性区域淋巴结清扫。本文回顾了头颈部皮肤恶性黑色素瘤的相关文献，并强调了该区域病变特有的手术和病理问题。
