Danieluk-Gil I
Arch Immunol Ther Exp (Warsz). 1975;23(2):263-76.
Phagocytosis was studied in exudative microphages from white mice with alloxan diabetes and insulin-induced hypoglycemia. Peritoneal exudates were induced to obtain exudative forms of microphages, which were used to phagocytize Staphylococcus aureus 209 P Oxford. Phagocytic indices were calculated by the method of Davies. The liver and pancreas were studied morphologically and histochemically, and serum glucose levels were assayed. The experiments showed that: 1) lowered phagocytic indices in animals with alloxan diabetes and insulin-induced hypoglycemia indicate lower phagocytic capability of exudative microphages; 2) normal phagocytosis depends on: a) normal blood levels of glucose as energetic material, and b) adequate concentration of insulin in tissues as enzymatic "transporter" of glucose.
对患有四氧嘧啶糖尿病和胰岛素诱导性低血糖的小白鼠渗出性巨噬细胞的吞噬作用进行了研究。诱导腹膜渗出以获得巨噬细胞的渗出形式，用于吞噬金黄色葡萄球菌209P牛津株。采用戴维斯方法计算吞噬指数。对肝脏和胰腺进行形态学和组织化学研究，并测定血清葡萄糖水平。实验表明：1）患有四氧嘧啶糖尿病和胰岛素诱导性低血糖的动物吞噬指数降低，表明渗出性巨噬细胞的吞噬能力较低；2）正常吞噬作用取决于：a）作为能量物质的葡萄糖的正常血液水平，以及b）组织中作为葡萄糖酶促“转运体”的胰岛素的适当浓度。
