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The distribution and metabolism of acrylamide and its neurotoxic analogues in rats.

作者信息

Edwards P M

出版信息

Biochem Pharmacol. 1975 Jul 15;24(13-14):1277-82. doi: 10.1016/0006-2952(75)90336-6.

DOI:10.1016/0006-2952(75)90336-6
PMID:1148016
Abstract
摘要

相似文献

1
The distribution and metabolism of acrylamide and its neurotoxic analogues in rats.
Biochem Pharmacol. 1975 Jul 15;24(13-14):1277-82. doi: 10.1016/0006-2952(75)90336-6.
2
Conjugation of acrylamide with glutathione catalysed by glutathione-S-transferases of rat liver and brain.大鼠肝脏和大脑中的谷胱甘肽-S-转移酶催化丙烯酰胺与谷胱甘肽的结合反应。
Biochem Pharmacol. 1981 Jul 1;30(13):1739-44. doi: 10.1016/0006-2952(81)90003-4.
3
Excretion of methyl mercury in rat bile: the effect of diethylmaleate, cyclohexene oxide and acrylamide.
Acta Pharmacol Toxicol (Copenh). 1978 Feb;42(2):135-41. doi: 10.1111/j.1600-0773.1978.tb02181.x.
4
Determination of acrylamide in rat serum and sciatic nerve by gas chromatography-electron-capture detection.气相色谱-电子捕获检测法测定大鼠血清和坐骨神经中的丙烯酰胺。
J Chromatogr. 1993 Sep 22;619(2):223-34. doi: 10.1016/0378-4347(93)80111-g.
5
Synergistic neurotoxic effects of styrene oxide and acrylamide: glutathione-independent necrosis of cerebellar granule cells.氧化苯乙烯和丙烯酰胺的协同神经毒性作用:小脑颗粒细胞不依赖谷胱甘肽的坏死
Toxicol Appl Pharmacol. 1993 Feb;118(2):233-44. doi: 10.1006/taap.1993.1029.
6
Determination of acrylamide in nerve tissue homogenates by electron-capture gas chromatography.采用电子捕获气相色谱法测定神经组织匀浆中的丙烯酰胺。
J Chromatogr. 1981 Nov 6;217:239-45. doi: 10.1016/s0021-9673(00)88078-4.
7
Metabolism of acrylamide into urinary mercapturic acid and cysteine conjugates in rats.大鼠体内丙烯酰胺代谢生成尿中硫醚氨酸和半胱氨酸共轭物的过程。
Drug Metab Dispos. 1982 Mar-Apr;10(2):196-7.
8
Alteration of amino acid incorporation into proteins of the nervous system in vitro after administration of acrylamide to rats.
Biochem Pharmacol. 1973 May 1;22(9):1057-66. doi: 10.1016/0006-2952(73)90170-6.
9
Pharmacokinetics of acrylamide in Fisher-344 rats.丙烯酰胺在费希尔344大鼠体内的药代动力学
Toxicol Appl Pharmacol. 1982 Mar 30;63(1):36-44. doi: 10.1016/0041-008x(82)90024-2.
10
Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acrylonitrile for 1 or 5 days.将丙烯酰胺和丙烯腈共同给予F344大鼠和B6C3F1小鼠1天或5天后的尿液代谢产物。
Chem Res Toxicol. 1997 Oct;10(10):1152-60. doi: 10.1021/tx9602123.

引用本文的文献

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Dosimetry of Acrylamide and Glycidamide Over the Lifespan in a 2-Year Bioassay of Acrylamide in Wistar Han Rats.在对Wistar Han大鼠进行的为期两年的丙烯酰胺生物测定中丙烯酰胺和缩水甘油酰胺在整个生命周期内的剂量测定
Toxicol Sci. 2015 Aug;146(2):386-94. doi: 10.1093/toxsci/kfv104. Epub 2015 Jul 3.
2
Synthesis and characterization of biodegradable poly (ethylene glycol) and poly (caprolactone diol) end capped poly (propylene fumarate) cross linked amphiphilic hydrogel as tissue engineering scaffold material.合成与表征可生物降解的聚乙二醇和聚己内酯二醇封端的聚(丙交酯-富马酸)交联两亲水凝胶作为组织工程支架材料。
J Mater Sci Mater Med. 2009 Dec;20 Suppl 1:S115-22. doi: 10.1007/s10856-008-3493-3. Epub 2008 Jun 27.
3
Studies on in vitro metabolism of acrylamide and related compounds.
丙烯酰胺及相关化合物的体外代谢研究。
Arch Toxicol. 1981 Sep;48(2-3):157-66. doi: 10.1007/BF00310484.
4
Neurotoxicity of acrylamide and related compounds and their effects on male gonads in mice.丙烯酰胺及相关化合物的神经毒性及其对小鼠雄性性腺的影响。
Arch Toxicol. 1981 Jun;47(3):179-89. doi: 10.1007/BF00368678.
5
Anemia and porphyria caused by N,N'-methylene-bis-acrylamide (MBA) in mice and rats.N,N'-亚甲基双丙烯酰胺(MBA)在小鼠和大鼠中引起的贫血和卟啉症。
Arch Toxicol. 1982 May;50(1):47-55. doi: 10.1007/BF00569236.
6
Effect of acrylamide on glutathione-S-transferase activity in different regions of rat brain.
Bull Environ Contam Toxicol. 1984 Feb;32(2):166-70. doi: 10.1007/BF01607480.
7
Neurotoxicity of acrylamide and related compounds in rats. Effects on rotarod performance, morphology of nerves and neurotubulin.丙烯酰胺及相关化合物对大鼠的神经毒性。对转棒试验表现、神经形态和神经微管蛋白的影响。
Arch Toxicol. 1983 Nov;54(3):203-13. doi: 10.1007/BF01239204.
8
Inhibition of brain enolases by acrylamide and its related compounds in vitro, and the structure-activity relationship.丙烯酰胺及其相关化合物对脑烯醇化酶的体外抑制作用及其构效关系。
Experientia. 1984 Sep 15;40(9):971-2. doi: 10.1007/BF01946464.
9
Neurofilament degradation in the nervous system of rats intoxicated with acrylamide, related compounds or 2,5-hexanedione.丙烯酰胺、相关化合物或2,5-己二酮中毒大鼠神经系统中的神经丝降解
Arch Toxicol. 1988 Aug;62(1):70-5. doi: 10.1007/BF00316261.
10
Sensitivity of transglutaminase in rat tissues to administration of acrylamide in vivo.大鼠组织中转谷氨酰胺酶对体内丙烯酰胺给药的敏感性。
Arch Toxicol. 1990;64(6):509-10. doi: 10.1007/BF01977637.