Britt B A, Endrenyi L, Barclay R L, Cadman D L
Br J Anaesth. 1975 Jun;47(6):647-53. doi: 10.1093/bja/47.6.647.
Total calcium content of both human and porcine MHS skeletal muscle is significantly less than normal. This data is consistent with the concept that some organelle (probably the sarcoplasmic reticulum, the mitochondrion or even the sarcolemma) within the MHS muscle stores less than normal amounts of calcium. The large variability between muscle specimens rules out measurement of total calcium content of skeletal muscle as a routine diagnostic test for malignant hyperthermia susceptibility.
人类和猪的恶性高热易感（MHS）骨骼肌的总钙含量显著低于正常水平。该数据与以下概念一致，即MHS肌肉内的某些细胞器（可能是肌浆网、线粒体甚至肌膜）储存的钙量低于正常水平。肌肉样本之间的巨大差异排除了将骨骼肌总钙含量的测量作为恶性高热易感性常规诊断测试的可能性。
