Pitrák V, Hadacová I, Hochová I, Hoch J
Chirurgická klinika 2. LF UK a FNM, Praha.
Rozhl Chir. 2001 Jun;80(6):290-3.
Chronic anticoagulant treatment is administered mostly for cardiological reasons. Cumarin derivatires are used in the majority of cases (Warfarin, Pelentan). It is necessary to monitor this treatment regularly and to control the dose according to the INR value. Different complications can occur; the haemorrhage represents a serious one. The authors discuss several aspects of anticoagulant therapy and possible prevention of the complications. The importance of the problems is demonstrated on the authors' clinical experience--two cases of haemorrhage after Warfarin administration simulating an acute surgical event.
长期抗凝治疗主要是出于心脏病学方面的原因而进行。在大多数情况下使用香豆素衍生物(华法林、苯丙香豆素)。必须定期监测这种治疗,并根据国际标准化比值(INR)值控制剂量。可能会出现不同的并发症;出血是一种严重的并发症。作者讨论了抗凝治疗的几个方面以及并发症的可能预防措施。通过作者的临床经验——两例服用华法林后出血模拟急性外科事件,证明了这些问题的重要性。